ArticleBMC geriatrics2022
Development, validation, and visualization of a web-based nomogram to predict 5-year mortality risk in older adults with hypertension.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 11 citations in OpenAlex.
- Predictive nomogram for abdominal aortic calcification risk: a multi-algorithm approach integrating demographic and clinical variables.Journal of cardiothoracic surgery · 2026Article
- Development and internal validation of a nomogram for predicting postoperative hypotension after carotid endarterectomy.Frontiers in surgery · 2026Article
- Predictors of one-year clinically driven revascularization following endovascular treatment of isolated atherosclerotic popliteal artery lesions.Scientific reports · 2025Article
- Construction of a nomogram for predicting the risk of all-cause mortality in patients with diabetic retinopathy.Frontiers in endocrinology · 2025Article
- Development and validation of a risk score nomogram model to predict the risk of 5-year all-cause mortality in diabetic patients with hypertension: A study based on NHANES data.International journal of cardiology. Cardiovascular risk and prevention · 2024Article
- Navigating the future of diabetes: innovative nomogram models for predicting all-cause mortality risk in diabetic nephropathy.BMC nephrology · 2024Article
- Unveiling the Hidden Burden: Estimating All-Cause Mortality Risk in Older Individuals with Type 2 Diabetes.Journal of diabetes research · 2024Article
- Association Between Self-Perception of Aging and Long-Term Mortality in Elderly Patients with Hypertension in Rural China: A Possible Beneficial Effect of Nut Intake.Clinical interventions in aging · 2024Article
- A glimpse into the future: revealing the key factors for survival in cognitively impaired patients.Frontiers in aging neuroscience · 2024Article
- Innovative nomogram for predicting 1-year clinically driven revascularization outcomes in endovascular femoropopliteal disease.Frontiers in cardiovascular medicine · 2024Article
- Development and validation of a nomogram for predicting all-cause mortality in American adult hypertensive populations.Frontiers in pharmacology · 2023Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension-related mortality has been increasing in older adults, resulting in serious burden to society and individual. However, how to identify older adults with hypertension at high-risk mortality remains a great challenge. The purpose of this study is to develop and validate the prediction nomogram for 5-year all-cause mortality in older adults with hypertension.
methodsData were extracted from National Health and Nutrition Examination Survey (NHANES). We recruited 2691 participants aged 65 years and over with hypertension in the NHANES 1999-2006 cycles (training cohort) and 1737 participants in the NHANES 2007-2010 cycles (validation cohort). The cohorts were selected to provide at least 5 years follow-up for evaluating all-cause mortality by linking National Death Index through December 31, 2015. We developed a web-based dynamic nomogram for predicting 5-year risk of all-cause mortality based on a logistic regression model in training cohort. We conducted internal validation by 1000 bootstrapping resamples and external validation in validation cohort. The discrimination and calibration of nomogram were evaluated using concordance index (C-index) and calibration curves.
resultsThe final model included eleven independent predictors: age, sex, diabetes, cardiovascular disease, body mass index, smoking, lipid-lowering drugs, systolic blood pressure, hemoglobin, albumin, and blood urea nitrogen. The C-index of model in training and validation cohort were 0.759 (bootstrap-corrected C-index 0.750) and 0.740, respectively. The calibration curves also indicated that the model had satisfactory consistence in two cohorts. A web-based nomogram was established ( https://hrzhang1993.shinyapps.io/dynnomapp ).
conclusionsThe novel developed nomogram is a useful tool to accurately predict 5-year all-cause mortality in older adults with hypertension, and can provide valuable information to make individualized intervention.
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