ArticleBMC plant biology2022
Anthocyanin regulatory networks in Solanum tuberosum L. leaves elucidated via integrated metabolomics, transcriptomics, and StAN1 overexpression.
Article in BMC plant biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 31 citations in OpenAlex.
- Article
- Transcriptome Dynamics Reveal the Potential Roles of Long Non-Coding RNAs in Regulating Flower Color of Safflowers (International journal of molecular sciences · 2026Article
- Coordinated changes in anthocyanins and cuticular wax during leaf color transition in Rosa chinensis.Scientific reports · 2026Article
- Integrated analysis of transcriptome sequencing and metabolomics provides insights into the molecular response ofFrontiers in microbiology · 2026Article
- Integration of multi-omics data and phenotyping provides insights into purple leaf sheaths color in millet seedling stage.BMC plant biology · 2025Article
- Transcriptomic and Metabolic Profiles of Apple Peels of Different Colors.Plants (Basel, Switzerland) · 2025Article
- Integrative metabolomic and transcriptomic analysis provides insight into the mechanism of pigmentation in potato tuber eyes.BMC plant biology · 2025Article
- Identification and Quantification of Anthocyanins in Various Organs of Potato Varieties (Plants (Basel, Switzerland) · 2025Article
- Genome-Wide Characterization ofInternational journal of molecular sciences · 2025Article
- A k-mer-based bulked segregant analysis approach to map seed traits in unphased heterozygous potato genomes.G3 (Bethesda, Md.) · 2024Article
- Enhanced UV-B Radiation in Potato Stems and Leaves Promotes the Accumulation of Anthocyanins in Tubers.Current issues in molecular biology · 2023Article
- Cyanidin-3-O-glucoside Contributes to Leaf Color Change by Regulating TwoInternational journal of molecular sciences · 2023Article
- Metabolome analysis reveals flavonoid changes during the leaf color transition inFrontiers in plant science · 2023Article
- Integration of comparative transcriptomics and WGCNA characterizes the regulation of anthocyanin biosynthesis in mung bean (Frontiers in plant science · 2023Article
- Long non-coding RNA-mediated competing endogenous RNA regulatory network during flower development and color formation inFrontiers in plant science · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnthocyanins, which account for color variation and remove reactive oxygen species, are widely synthesized in plant tissues and organs. Using targeted metabolomics and nanopore full-length transcriptomics, including differential gene expression analysis, we aimed to reveal potato leaf anthocyanin biosynthetic pathways in different colored potato varieties.
resultsMetabolomics analysis revealed 17 anthocyanins. Their levels varied significantly between the different colored varieties, explaining the leaf color differences. The leaves of the Purple Rose2 (PurpleR2) variety contained more petunidin 3-O-glucoside and malvidin 3-O-glucoside than the leaves of other varieties, whereas leaves of Red Rose3 (RedR3) contained more pelargonidin 3-O-glucoside than the leaves of other varieties. In total, 114 genes with significantly different expression were identified in the leaves of the three potato varieties. These included structural anthocyanin synthesis-regulating genes such as F3H, CHS, CHI, DFR, and anthocyanidin synthase and transcription factors belonging to multiple families such as C3H, MYB, ERF, NAC, bHLH, and WRKY. We selected an MYB family transcription factor to construct overexpression tobacco plants; overexpression of this factor promoted anthocyanin accumulation, turning the leaves purple and increasing their malvidin 3-o-glucoside and petunidin 3-o-glucoside content.
conclusionsThis study elucidates the effects of anthocyanin-related metabolites on potato leaves and identifies anthocyanin metabolic network candidate genes.
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