Evidence map›Paper›PMID 35508966›Full record

ArticleBMC genomics2022

Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle.

Wai Yee Low, Benjamin D Rosen, Yan Ren, Derek M Bickhart, Thu-Hien To, Fergal J Martin, Konstantinos Billis, Tad S Sonstegard, Shawn T Sullivan, Stefan Hiendleder and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Sea CucumberResearch square · 2026
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  5. Frontiers in veterinary science · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Wai Yee LowThe Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA, 5371, Australia. wai.low@adelaide.edu.au.
Benjamin D RosenAnimal Genomics and Improvement LaboratoryARS USDA, Beltsville, MD, USA.
Yan RenThe Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA, 5371, Australia.
Derek M BickhartDairy Forage Research Center, ARS USDA, Madison, WI, USA.
Thu-Hien ToNorwegian University of Life Sciences: NMBU, Universitetstunet 3, 1430, Ås, Norway.
Fergal J MartinEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Konstantinos BillisEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Tad S SonstegardAcceligen (United States), St. Paul, MN, USA.
Shawn T SullivanPhase Genomics, 4000 Mason Road, Suite 225, Seattle, WA, 98195, USA.
Stefan HiendlederThe Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA, 5371, Australia.
John L WilliamsThe Davies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA, 5371, Australia.
Michael P HeatonU.S. Department of Agriculture, Agricultural Research Service, U.S. Meat Animal Research Center, Clay Center, Nebraska, USA.
Timothy P L SmithU.S. Department of Agriculture, Agricultural Research Service, U.S. Meat Animal Research Center, Clay Center, Nebraska, USA. tim.smith2@usda.gov.
University of Adelaide · AUEuropean Bioinformatics Institute · GBAgricultural Research Service · USID Genomics (United States) · USNorwegian University of Life Sciences · NORoman L. Hruska U.S. Meat Animal Research Center · USUniversità Cattolica del Sacro Cuore · ITU.S. Dairy Forage Research Center · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundThe gaur (Bos gaurus) is the largest extant wild bovine species, native to South and Southeast Asia, with unique traits, and is listed as vulnerable by the International Union for Conservation of Nature (IUCN).

resultsWe report the first gaur reference genome and identify three biological pathways including lysozyme activity, proton transmembrane transporter activity, and oxygen transport with significant changes in gene copy number in gaur compared to other mammals. These may reflect adaptation to challenges related to climate and nutrition. Comparative analyses with domesticated indicine (Bos indicus) and taurine (Bos taurus) cattle revealed genomic signatures of artificial selection, including the expansion of sperm odorant receptor genes in domesticated cattle, which may have important implications for understanding selection for male fertility.

conclusionsApart from aiding dissection of economically important traits, the gaur genome will also provide the foundation to conserve the species.

Indexed as

Receptors, OdorantAnimalsCattleGenomeGenomicsMaleMammalsSpermatozoaZona Pellucida GlycoproteinsReceptors, OdorantZona Pellucida GlycoproteinsDomesticationGaurGenome assemblyOdorant receptorsSperm

Identifiers

PMID35508966
PMCPMC9069736
OpenAlexW4225396426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.