Evidence map›Paper›PMID 35508713›Full record

ArticleCommunications biology2022

PGC1 alpha coactivates ERG fusion to drive antioxidant target genes under metabolic stress.

Aiindrila Dhara, Imlimaong Aier, Ankush Paladhi, Pritish Kumar Varadwaj, Sumit Kumar Hira, Nirmalya Sen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Aiindrila DharaMolecular oncology laboratory, S.N. Bose innovation centre, University of Kalyani, Kalyani, West Bengal, 741235, India.
Imlimaong AierDepartment of Bioinformatics & Applied Sciences, Indian Institute of Information Technology-, Allahabad, Uttar Pradesh, 211012, India.
Ankush PaladhiCellular Immunology Laboratory, Department of Zoology, The University of Burdwan, Burdwan, West Bengal, 713104, India.ORCID 0000-0003-4001-0484
Pritish Kumar VaradwajDepartment of Bioinformatics & Applied Sciences, Indian Institute of Information Technology-, Allahabad, Uttar Pradesh, 211012, India.
Sumit Kumar HiraCellular Immunology Laboratory, Department of Zoology, The University of Burdwan, Burdwan, West Bengal, 713104, India.ORCID 0000-0001-6113-4721
Nirmalya SenMolecular oncology laboratory, S.N. Bose innovation centre, University of Kalyani, Kalyani, West Bengal, 741235, India. nirmalyarffs19@klyuniv.ac.in.ORCID 0000-0002-8441-001X
Indian Institute of Information Technology Allahabad · INUniversity of Burdwan · INUniversity of Kalyani · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of ERG gene fusion; from developing prostatic intraepithelial neoplasia (PIN) lesions to hormone resistant high grade prostate cancer (PCa) dictates disease progression, altered androgen metabolism, proliferation and metastasis

Indexed as

AntioxidantsPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaProstatic NeoplasmsAndrogensGene FusionHumansMaleStress, PhysiologicalTranscriptional Regulator ERGAndrogensAntioxidantsERG protein, humanPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaTranscriptional Regulator ERG

Identifiers

PMID35508713
PMCPMC9068611
OpenAlexW4225415062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.