Evidence map›Paper›PMID 35508679›Full record

ArticleMaternal and child health journal2022

Influence of Maternal Childhood Trauma on Perinatal Depression, Observed Mother-Infant Interactions, and Child Growth.

Karmel W Choi, Christy A Denckla, Nadia Hoffman, Shrish Budree, Liz Goddard, Heather J Zar, Micky Stern, Dan J Stein

Open access · greenAbstract read
In one paragraph

Article in Maternal and child health journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. When a Parent Is Born: An Integrated Approach to Perinatal Mental Health and Early Risk Screening.European journal of investigation in health, psychology and education · 2025
    Article
  3. Associations of maternal alcohol and non-prescribed substance use with early child growth.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Karmel W ChoiDepartment of Psychiatry, Massachusetts General Hospital, Boston, USA. kwchoi@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-3914-2431
Christy A DencklaDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, USA.
Nadia HoffmanDepartment of Psychiatry and Mental Health, University of Cape Town, Groote Schuur Hospital J2, Anzio Road, Observatory, Cape Town, 7925, South Africa.
Shrish BudreeUnit on Child and Adolescent Health, South African Medical Research Council, Cape Town, South Africa.
Liz GoddardUnit on Child and Adolescent Health, South African Medical Research Council, Cape Town, South Africa.
Heather J ZarUnit on Child and Adolescent Health, South African Medical Research Council, Cape Town, South Africa.
Micky SternDepartment of Psychiatry and Mental Health, University of Cape Town, Groote Schuur Hospital J2, Anzio Road, Observatory, Cape Town, 7925, South Africa.
Dan J SteinDepartment of Psychiatry and Mental Health, University of Cape Town, Groote Schuur Hospital J2, Anzio Road, Observatory, Cape Town, 7925, South Africa. dan.stein@uct.ac.za.
South African Medical Research Council · ZAUniversity of Cape Town · ZABoston University · USHarvard University · US

Funding

Pathogenic mechanisms in post-bereavement psychopathology: Contributions of gene-environment interplay, psychosocial factors, and cognitive ability in two population-based cohortsK23MH117278 · NIMH · HARVARD SCHOOL OF PUBLIC HEALTH · PI DENCKLA, CHRISTY ANN · 2019 to 2023
$942k
Harvard T.H. Chan School of Public Health BiostatisticsHarvard T.H. Chan School of Public Health Rose Traveling Fellowship Program in Chronic Disease EpidemiologyNIMH NIH HHS K23 MH117278
6 · The paper itself

Abstract

introductionMothers who have experienced childhood trauma may be at increased risk for disruptions in caregiving behavior, with potential consequences for early child development. However, assessments of caregiving behavior tend to be self-reported, which may bias results, and have been limited in lower-resource settings.

methodsIn an overall sample of 256 South African mothers followed across the perinatal period, this longitudinal study used structural equation modeling to test pathways of association between maternal childhood trauma and depressive symptoms on observed mother-infant interactions at 3.5 months and subsequent child growth outcomes at 1 year.

resultsOn average, mothers with childhood trauma histories tended to show lower rated overall interactions with their infants (B = - 0.16, p = .013), which in turn was associated with reduced child growth at 1 year (B = 0.17, p = .046). When this model was adjusted for maternal age and relative socioeconomic status (SES), maternal SES strongly explained child growth (B = 0.31, p < .001) such that the direct effect of mother-infant interactions was no longer significant. DISCUSSION: For child growth in a lower-resource setting, quality of mother-infant interactions could be a relevant predictor but more strongly explained by maternal SES factors, suggesting a need for broader approaches that not only improve dyadic relationships but also address maternal ecological resources.

Indexed as

Adverse Childhood ExperiencesDepression, PostpartumChildDepressionFemaleHumansInfantLongitudinal StudiesMother-Child RelationsMothersPregnancyChildhood traumaMother–infant bondingObservationalPostpartum depressionSouth Africa

Identifiers

PMID35508679
PMCPMC9826718
OpenAlexW4229016907

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.