Evidence map›Paper›PMID 35508650›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2022

"Reverse roussouly": cervicothoracic curvature ratios define characteristic shapes in adult cervical deformity.

Peter G Passias, Katherine E Pierce, Tyler Williamson, Shaleen Vira, Stephane Owusu-Sarpong, Ravinderjit Singh, Oscar Krol, Lara Passfall, Nicholas Kummer, Bailey Imbo and 10 more

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Peter G PassiasDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA. Peter.Passias@nyumc.org.ORCID 0000-0002-1479-4070
Katherine E PierceDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Tyler WilliamsonDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Shaleen ViraDepartment of Orthopedic and Neurosurgery, UT Southwestern Medical Center, Dallas, TX, USA.
Stephane Owusu-SarpongDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Ravinderjit SinghDepartment of Orthopedic and Neurosurgery, UT Southwestern Medical Center, Dallas, TX, USA.
Oscar KrolDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Lara PassfallDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Nicholas KummerDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Bailey ImboDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Rachel Joujon-RocheDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Peter TretiakovDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Kevin MoattariDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Matthew V AbolaDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Waleed AhmadDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Sara NaessigDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Salman AhmadDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Vivek SinghDivision of Spinal Surgery, Department of Orthopaedic and Neurological Surgery, NYU Langone Medical Center, New York Spine Institute, Orthopaedic Hospital - NYU School of Medicine, 301 East 17th St, New York, NY, 10003, USA.
Bassel DieboDepartment of Orthopedics, SUNY Downstate, Brooklyn, NY, USA.
Virginie LafageDepartment of Orthopaedics, Lenox Hill Hospital, Northwell Health, New York, NY, USA.
NYU Langone Health · USSouthwestern Medical CenterNorthwell Health · USSUNY Downstate Health Sciences University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate normal curvature ratios of the cervicothoracic spine and to establish radiographic thresholds for severe myelopathy and disability, within the context of shape.

methodsAdult cervical deformity (CD) patients undergoing cervical fusion were included. C2-C7 Cobb angle (CL) and thoracic kyphosis (TK), using T2-T12 Cobb angle, were used as a ratio, ranging from -1 to + 1. Pearson bivariate r and univariate analyses analyzed radiographic correlations and differences in myelopathy(mJOA > 14) or disability(NDI > 40) across ratio groups.

resultsSixty-three CD patients included. Regarding CL:TK ratio, 37 patients had a negative ratio and 26 patients had a positive ratio. A more positive CL:TK correlated with increased TS-CL(r = 0.655, p =  < 0.001)and mJOA(r = 0.530, p = 0.001), but did not correlate with cSVA/SVA or NDI scores. A positive CL:TK ratio was associated with moderate disability(NDI > 40)(OR: 7.97[1.22-52.1], p = 0.030). Regression controlling for CL:TK ratio revealed cSVA > 25 mm increased the odds of moderate to severe myelopathy and cSVA > 30 mm increased the odds of significant neck disability. Lastly, TS-CL > 29 degrees increased the odds of neck disability by 4.1 × with no cutoffs for severe mJOA(p > 0.05).

conclusionsCervical deformity patients with an increased CL:TK ratio had higher rates of moderate neck disability at baseline, while patients with a negative ratio had higher rates of moderate myelopathy clinically. Specific thresholds for cSVA and TS-CL predicted severe myelopathy or neck disability scores, regardless of baseline neck shape. A thorough evaluation of the cervical spine should include exploration of relationships with the thoracic spine and may better allow spine surgeons to characterize shapes and curves in cervical deformity patients.

Indexed as

KyphosisSpinal Cord DiseasesAdultCervical VertebraeHumansNeckQuality of LifeCervical deformityCervicothoracicMyelopathyRoussoulySecondary driverSpine

Identifiers

PMID35508650
OpenAlexW4229011225

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.