Evidence map›Paper›PMID 35508541›Full record

ArticleNature communications2022

The dopamine transporter antiports potassium to increase the uptake of dopamine.

Solveig G Schmidt, Mette Galsgaard Malle, Anne Kathrine Nielsen, Søren S-R Bohr, Ciara F Pugh, Jeppe C Nielsen, Ida H Poulsen, Kasper D Rand, Nikos S Hatzakis, Claus J Loland

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Control of Conformational Transitions by the Conserved GXInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Identification of the potassium-binding site in serotonin transporter.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Article
  16. Review
  17. Exploring the KeLife · 2024
    Article
  18. Single-Particle Tracking ofBiomolecules · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Solveig G SchmidtLaboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-4771-1227
Mette Galsgaard Malle *Nano-Science Center, Department of Chemistry, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-3722-502X
Anne Kathrine Nielsen *Laboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Søren S-R BohrNano-Science Center, Department of Chemistry, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-8107-2465
Ciara F PughLaboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jeppe C NielsenLaboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-0678-3689
Ida H PoulsenLaboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kasper D RandProtein Analysis Group, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-6337-5489
Nikos S HatzakisNano-Science Center, Department of Chemistry, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Claus J LolandLaboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. cllo@sund.ku.dk.ORCID 0000-0002-1773-1446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dopamine transporter facilitates dopamine reuptake from the extracellular space to terminate neurotransmission. The transporter belongs to the neurotransmitter:sodium symporter family, which includes transporters for serotonin, norepinephrine, and GABA that utilize the Na

Indexed as

Dopamine Plasma Membrane Transport ProteinsSymportersAnimalsDopamineDrosophilaIonsIon TransportNeurotransmitter AgentsPotassiumSerotonin Plasma Membrane Transport ProteinsSodiumDopamineDopamine Plasma Membrane Transport ProteinsIonsNeurotransmitter AgentsPotassiumSerotonin Plasma Membrane Transport ProteinsSodiumSymporters

Identifiers

PMID35508541
PMCPMC9068915

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.