Evidence map›Paper›PMID 35508031›Full record

ArticleBrazilian dental journal

Physicochemical properties and penetration into dentinal tubules of calcium hypochlorite with surfactants.

Hernán Coaguila-Llerena, Julia da Silva Toledo, Ana Paula Ramos, Gisele Faria

Abstract read
In one paragraph

Article in Brazilian dental journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hernán Coaguila-LlerenaDepartment of Restorative Dentistry, São Paulo State University(UNESP), School of Dentistry, Araraquara, SP, Brazil.ORCID http://orcid.org/0000-0002-9991-718X
Julia da Silva ToledoDepartment of Restorative Dentistry, São Paulo State University(UNESP), School of Dentistry, Araraquara, SP, Brazil.ORCID http://orcid.org/0000-0001-8421-1347
Ana Paula RamosDepartment of Chemistry, Ribeirão Preto College of Philosophy Sciences and Letters, São Paulo University(USP), Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0000-0001-6200-8989
Gisele FariaDepartment of Restorative Dentistry, São Paulo State University(UNESP), School of Dentistry, Araraquara, SP, Brazil.ORCID http://orcid.org/0000-0001-7030-3718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim was to assess the physicochemical properties and the penetration into dentinal tubules of calcium hypochlorite solution [Ca(OCl)2], with or without surfactants. The surfactants benzalkonium chloride, cetrimide, Tween 80 and Triton X-100 were mixed at different concentrations with sodium hypochlorite solution (NaOCl), Ca(OCl)2 and distilled water (control). Once the critical micellar concentration (CMC) of the surfactants in Ca(OCl)2 and NaOCl was determined, pH, free chlorine, surface tension and free calcium ions were evaluated. The penetration into dentinal tubules of NaOCl and Ca(OCl)2, with or without benzalkonium chloride and Triton X-100 [surfactants that promoted the lowest surface tension of Ca(OCl)2], was assessed using human premolars stained with crystal violet. The statistical tests were one-way ANOVA and Tukey's post-test, Kruskal-Wallis and Dunn's post-test, two-way ANOVA and Bonferroni's post-test, and t-test; depending on the assay. The addition of surfactants reduced the surface tension of NaOCl and Ca(OCl)2, and did not alter the pH or the free available chlorine of either solution. The addition of all surfactants increased the availability of free calcium ions in Ca(OCl)2, especially benzalkonium chloride. Ca(OCl)2 exhibited lower penetration into dentinal tubules than NaOCl, and the addition of surfactants did not improve the penetration of Ca(OCl)2, but did increase the penetration of NaOCl. It can be concluded that the addition of surfactants to Ca(OCl)2 did not increase the penetration into dentinal tubules, but it did promote lower surface tension, without changing the pH or free available chlorine values, and higher availability of free calcium ions in Ca(OCl)2.

Indexed as

Root Canal IrrigantsSodium HypochloriteBenzalkonium CompoundsCalciumCalcium CompoundsChlorineHumansOctoxynolSurface-Active AgentsBenzalkonium CompoundsCalciumCalcium Compoundscalcium hypochloriteChlorineOctoxynolRoot Canal IrrigantsSodium HypochloriteSurface-Active Agents

Identifiers

PMID35508031
PMCPMC9645156

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.