Evidence map›Paper›PMID 35507969›Full record

ArticleActa cirurgica brasileira2022

Immunomodulatory effects of Blaps rynchopetera extract.

Di Meng, Yinhe Yang, Longxing Li, Xiaoli Qian, Qi Wang, Jinglei Xu, Hairong Zhao, Heng Liu, Huai Xiao, Zhongtao Ding

Open access · goldAbstract read
In one paragraph

Article in Acta cirurgica brasileira, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Chromosome-level genome assembly of the medicinal insect Blaps rhynchopetera using Nanopore and Hi-C technologies.DNA research : an international journal for rapid publication of reports on genes and genomes · 2024
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Di MengMaster. Dali University - College of Pharmacy - Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D - Dali, China.ORCID http://orcid.org/0000-0001-6218-2151
Yinhe YangPhD. Associate Professor. Dali University - College of Pharmacy - Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D - Dali, China.ORCID http://orcid.org/0000-0003-2792-8274
Longxing LiBS. Associate Professor. Dali University - Analysis and Testing Center - Dali, China.ORCID http://orcid.org/0000-0003-3097-3543
Xiaoli QianMaster. Dali University - College of Pharmacy - Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D - Dali, China.ORCID http://orcid.org/0000-0002-0614-9696
Qi WangMaster. Dali University - College of Pharmacy - Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D - Dali, China.ORCID http://orcid.org/0000-0001-9863-560X
Jinglei XuMaster. Dali University - College of Pharmacy - Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D - Dali, China.ORCID http://orcid.org/0000-0003-2101-4631
Hairong ZhaoMaster. Dali University - College of Pharmacy - Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D - Dali, China.ORCID http://orcid.org/0000-0003-0000-8136
Heng LiuMaster. Dali University - College of Pharmacy - Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D - Dali, China.ORCID http://orcid.org/0000-0003-3937-4985
Huai XiaoPhD. Professor. Dali University - College of Pharmacy - Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D - Dali, China.ORCID http://orcid.org/0000-0003-3427-2197
Zhongtao DingPhD. Professor. Dali University - College of Pharmacy - Dali, China, and Yunnan University - Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province - Kunming, China.ORCID http://orcid.org/0000-0002-5058-5663
Dali University · CNYunnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the potential immunomodulatory effects of total extract and different polar parts from Blaps rynchopetera Fairmaire.

methodsPhagocytic activity was evaluated by neutral red assay, and the effect of the immune function was investigated by normal and immunocompromised mice models.

resultsIn vitro, total extract, as well as chloroform, ethyl acetate, n-butanol and water fractions could individually enhance the phagocytic ability of mouse peritoneal macrophages; in addition, chloroform and ethyl acetate fractions had an increasing tendency when combined stimulation with lipopolysaccharide (LPS). In vivo, ethyl acetate fraction (EAF) could enhance the immune organ index, increase the serum hemolysin level and peripheral blood immune cells of immunocompromised mice, while for normal mice, the effect was inconspicuous.

conclusionsBlaps rynchopetera extracts had noteworthy immunomodulatory effect, especially for individuals with immune disorders.

Indexed as

ChloroformPlant ExtractsAnimalsImmunityLipopolysaccharidesMiceChloroformLipopolysaccharidesPlant Extracts

Identifiers

PMID35507969
PMCPMC9064186
OpenAlexW4285276943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.