Evidence map›Paper›PMID 35507806›Full record

ArticleAging2022

Single-cell transcriptomics reveals age-resistant maintenance of cell identities, stem cell compartments and differentiation trajectories in long-lived naked mole-rats skin.

Aleksandra Savina, Thierry Jaffredo, Frederic Saldmann, Chris G Faulkes, Philippe Moguelet, Christine Leroy, Delphine Del Marmol, Patrice Codogno, Lucy Foucher, Antoine Zalc and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Decay of Skin-Specific Gene Modules in Pangolins.Journal of molecular evolution · 2023
    Article
  3. Inflammation and aging: signaling pathways and intervention therapies.Signal transduction and targeted therapy · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Aleksandra SavinaUniversité Paris Cité, CNRS, INSERM, Institut Cochin, Paris, France.
Thierry JaffredoInstitut de Biologie Paris Seine (IBPS), Laboratoire de Biologie du Développement, Sorbonne Université, CNRS, INSERM, Paris, France.
Frederic SaldmannFondation pour la Recherche en Physiologie, Brussels, Belgium.
Chris G FaulkesQueen Mary University of London, School of Biological and Chemical Sciences, London, United Kingdom.
Philippe MogueletService d'Anatomie et Cytologie Pathologiques, Hôpital Tenon, Assistance Publique-Hôpitaux de Paris, Paris, France.
Christine LeroyUniversité Paris Cité, CNRS, INSERM, Institut Necker-Enfants Malades, Paris, France.
Delphine Del MarmolUniversité de Namur ASBL, Namur, Belgium.
Patrice CodognoUniversité Paris Cité, CNRS, INSERM, Institut Necker-Enfants Malades, Paris, France.
Lucy FoucherEcole Nationale Vétérinaire d'Alfort, Centre de Recherche Biomédicale, Maisons-Alfort, France.
Antoine ZalcUniversité Paris Cité, CNRS, INSERM, Institut Cochin, Paris, France.
Mélanie ViltardFondation pour la Recherche en Physiologie, Brussels, Belgium.
Gérard FriedlanderUniversité Paris Cité, CNRS, INSERM, Institut Necker-Enfants Malades, Paris, France.
Selim AractingiUniversité Paris Cité, CNRS, INSERM, Institut Cochin, Paris, France.
Romain H FontaineUniversité Paris Cité, CNRS, INSERM, Institut Cochin, Paris, France.
Centre National de la Recherche Scientifique · FRAssistance Publique – Hôpitaux de Paris · FRUniversité Paris Cité · FRÉcole Nationale Vétérinaire d'Alfort · FRInserm · FRQueen Mary University of London · GBUniversity of Namur · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naked mole-rats (NMR) are subterranean rodents characterized by an unusual longevity coupled with an unexplained resistance to aging. In the present study, we performed extensive

Indexed as

Mole RatsTranscriptomeAgingAnimalsLongevityMiceStem Cellsagingnaked mole-ratskinstem cellswound healing

Identifiers

PMID35507806
PMCPMC9134947
OpenAlexW4225376859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.