Evidence map›Paper›PMID 35507573›Full record

ArticleAngewandte Chemie (International ed. in English)2022

Towards Control and Oversight of SARS-CoV-2 Diagnosis and Monitoring through Multiplexed Quantitative Electroanalytical Immune Response Biosensors.

Rebeca M Torrente-Rodríguez, Ana Montero-Calle, Clara San Bartolomé, Olga Cano, Mónica Vázquez, María Iglesias-Caballero, Andrés Corral-Lugo, Michael J McConnell, Mariona Pascal, Vicente Mas and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Development of practical techniques for simultaneous detection and distinction of current and emerging SARS-CoV-2 variants.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
    Review
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Rebeca M Torrente-RodríguezDepartment of Analytical Chemistry, Faculty of Chemical Sciences, Complutense University of Madrid, 28040, Madrid, Spain.ORCID 0000-0002-2153-172X
Ana Montero-CalleChronic Disease Program (UFIEC), Instituto de Salud Carlos III, Majadahonda, 28220, Madrid, Spain.ORCID 0000-0001-5141-0454
Clara San BartoloméImmunology Department, Centre de Diagnòstic Biomèdic, Hospital Clínic de Barcelona, 08036, Barcelona, Spain.
Olga CanoRespiratory Viruses Laboratory, National Center for Microbiology, Instituto de Salud Carlos III, Majadahonda, 28220, Madrid, Spain.
Mónica VázquezRespiratory Viruses Laboratory, National Center for Microbiology, Instituto de Salud Carlos III, Majadahonda, 28220, Madrid, Spain.
María Iglesias-CaballeroRespiratory Viruses Laboratory, National Center for Microbiology, Instituto de Salud Carlos III, Majadahonda, 28220, Madrid, Spain.
Andrés Corral-LugoIntrahospital Infections Laboratory, National Center for Microbiology, Instituto de Salud Carlos III, Majadahonda, 28220, Madrid, Spain.
Michael J McConnellIntrahospital Infections Laboratory, National Center for Microbiology, Instituto de Salud Carlos III, Majadahonda, 28220, Madrid, Spain.
Mariona PascalImmunology Department, Centre de Diagnòstic Biomèdic, Hospital Clínic de Barcelona, 08036, Barcelona, Spain.
Vicente MasRespiratory Viruses Laboratory, National Center for Microbiology, Instituto de Salud Carlos III, Majadahonda, 28220, Madrid, Spain.
José M PingarrónDepartment of Analytical Chemistry, Faculty of Chemical Sciences, Complutense University of Madrid, 28040, Madrid, Spain.ORCID 0000-0003-2271-1383
Rodrigo BarderasChronic Disease Program (UFIEC), Instituto de Salud Carlos III, Majadahonda, 28220, Madrid, Spain.ORCID 0000-0003-3539-7469
Susana CampuzanoDepartment of Analytical Chemistry, Faculty of Chemical Sciences, Complutense University of Madrid, 28040, Madrid, Spain.ORCID 0000-0002-9928-6613
Instituto de Salud Carlos III · ESUniversidad Complutense de Madrid · ESHospital Clínic de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of versatile and sensitive biotools to quantify specific SARS-CoV-2 immunoglobulins in SARS-CoV-2 infected and non-infected individuals, built on the surface of magnetic microbeads functionalized with nucleocapsid (N) and in-house expressed recombinant spike (S) proteins is reported. Amperometric interrogation of captured N- and S-specific circulating total or individual immunoglobulin (Ig) isotypes (IgG, IgM, and IgA), subsequently labelled with HRP-conjugated secondary antibodies, was performed at disposable single or multiplexed (8×) screen-printed electrodes using the HQ/HRP/H

Indexed as

Biosensing TechniquesCOVID-19Antibodies, ViralCOVID-19 TestingHumansImmunityImmunoglobulin GSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, ViralImmunoglobulin GSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Electroanalytical BioplatformsImmune ResponseOmicronSARS-Cov-2Viral Antigens

Identifiers

PMID35507573
PMCPMC9348255
OpenAlexW4229017092

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.