Evidence map›Paper›PMID 35507503›Full record

ArticleClinical implant dentistry and related research2022

Tooth as graft material: Histologic study.

Elio Minetti, Stefano Corbella, Silvio Taschieri, Luigi Canullo

Abstract read
In one paragraph

Article in Clinical implant dentistry and related research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  13. Tooth as graft material: Histologic study.Clinical implant dentistry and related research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elio MinettiDepartment of Biomedical, Surgical, and Dental Science, Università degli Studi di Milano, Milan.ORCID https://orcid.org/0000-0002-4151-8063
Stefano CorbellaDepartment of Biomedical, Surgical, and Dental Science, Università degli Studi di Milano, Milan.
Silvio TaschieriDepartment of Biomedical, Surgical, and Dental Science, Università degli Studi di Milano, Milan.
Luigi CanulloDepartment of Periodontics and Implantology, University Of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0001-9875-2929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn effective regenerative protocol is key to reestablish and maintain the hard and soft tissue dimensions over time. The choice of the graft material and its properties also could have an impact on the results. To prevent alveolar ridge dimensional changes, since numerous graft materials have been suggested and in the past years, a growing interest in teeth material has been observed as a valuable alternative to synthetic biomaterials.

aimThe aim of the study was to explore the histomorphometric outcomes of tooth derivative materials as used as bone substitute material in socket preservation procedure.

methodsAfter alveolar socket preservation (ASP) procedures using autologous demineralized tooth as graft material prepared by means of an innovative device, was evaluated. A total of 101 histological samples, from 96 subjects, were analyzed by evaluating the total amount of bone (BV), residual tooth material (residual graft, TT), and vital bone (VB). The section from each sample was then split in nine subsections, resulting in 909 subsections, to allow statistical comparison between the different areas.

resultsIt was not noticed a statistically significant difference between maxillary and mandibular sites, being the amount of VB in upper jaw sites 37.9 ± 21.9% and 38.0 ± 22.0% in lower jaw sites and the amount of TT was 7.7 ± 12.2% in maxilla and 7.0 ± 11.1% in mandibles. None of the other considered parameters, including defect type and section position, were statistically correlated to the results of the histomorphometric analysis.

conclusionsASP procedure using demineralized autologous tooth-derived biomaterial may be a predictable procedure to produce new vital bone potentially capable to support dental implant rehabilitation.

Indexed as

Alveolar Ridge AugmentationBone SubstitutesAlveolar ProcessBone TransplantationHumansTooth ExtractionTooth SocketBone Substitutesalveolar ridge reconstructionautogenousbiomaterialsbonebone augmentationbone graftingbone substituteshistological analysisimplantologyprospective

Identifiers

PMID35507503
PMCPMC9544007

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.