SynthesisJAMA cardiology2022
Long-term Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-analysis.
Synthesis in JAMA cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- A meta-analysis of survival and prognostic factors in multiple system atrophy.Journal of neurology · 2025Pooled it
- Predicting Long-Term Cognitive Impairments in Survivors after Cardiac Arrest: A Systematic Review.Journal of rehabilitation medicine · 2023Pooled it
- Predicting neurological outcome in adult patients with cardiac arrest: systematic review and meta-analysis of prediction model performance.Critical care (London, England) · 2022Pooled it
- Comparison of video-assisted CPR using the LINE application and telephone-assisted CPR: a randomized controlled simulation trial.BMC emergency medicine · 2026Trial
- Combined effects of targeted blood pressure, oxygenation, and duration of device-based fever prevention after out-of-hospital cardiac arrest on 1-year survival: post hoc analysis of a randomized controlled trial.Critical care (London, England) · 2024Trial
- MicroRNA and Inflammatory Biomarker Signatures Associated With Neurological Outcome After Out-Of-Hospital Cardiac Arrest: The MiRacle Study.European journal of clinical investigation · 2026Article
- Cardiometabolic multimorbidity and survival after out-of-hospital cardiac arrest.Resuscitation plus · 2026Article
- Association of Serial Lactate-to-Albumin and C-Reactive Protein-to-Albumin Ratios with In-Hospital Mortality After Out-of-Hospital Cardiac Arrest.Journal of clinical medicine · 2026Article
- Predicting dynamic individual out-of-hospital cardiac arrest risks using explainable machine learning: a multicenter study in China.NPJ digital medicine · 2026Article
- Impact of establishing a new emergency and critical care center on regional out-of-hospital cardiac arrest transport patterns and outcomes.Resuscitation plus · 2026Article
- Barriers to action: behavioral determinants of bystander intervention in medical emergencies - a scoping review.BMC emergency medicine · 2026Article
- Prevalence and prognostic relevance of abnormal liver function tests in critically ill patients with cardiac arrest.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Successful use of methylene blue following out of hospital cardiac arrest: a case report.European heart journal. Case reports · 2026Article
- Cortical OProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Thrombolytic therapy efficacy in cardiopulmonary resuscitation: Investigating the effect of recombinant tissue plasminogen activator (Review).Molecular medicine reports · 2025Review
- Factors associated with recurrent out-of-hospital cardiac arrest after hospital discharge: a population-based study.Resuscitation plus · 2025Article
- Current Perspectives on Rehabilitation Following Return of Spontaneous Circulation After Sudden Cardiac Arrest: A Narrative Review.Healthcare (Basel, Switzerland) · 2025Review
- [Long-term Survivorship after Out-of-hospital Cardiac Arrest in the Republic of Korea].Jugan geon-gang gwa jilbyeong · 2025Article
- Smartphone-activated volunteer responders and survival to discharge after out-of-hospital cardiac arrests in Victoria, 2018-23: an observational cohort study.The Medical journal of Australia · 2025Observational
- Suitability of a Low-Fidelity and Low-Cost Simulator for Teaching Basic Cardiopulmonary Resuscitation-"Hands-Only CPR"-To Nursing Students.Nursing reports (Pavia, Italy) · 2025Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: Data on long-term survival beyond 12 months after out-of-hospital cardiac arrest (OHCA) of a presumed cardiac cause are scarce. Objective: To investigate the long-term survival of adult patients after surviving the initial hospital stay for an OHCA. Data Sources: A systematic search of the EMBASE and MEDLINE databases was performed from database inception to March 25, 2021. Study Selection: Clinical studies reporting long-term survival after OHCA were selected based on predefined inclusion and exclusion criteria according to a preregistered study protocol. Data Extraction and Synthesis: Patient data were reconstructed from Kaplan-Meier curves using an iterative algorithm and then pooled to generate survival curves. As a separate analysis, an aggregate data meta-analysis was performed. Main Outcomes and Measures: The primary outcome was long-term survival (>12 months) after OHCA for patients surviving to hospital discharge or 30 days after OHCA. Results: The search identified 15 347 reports, of which 21 studies (11 800 patients) were included in the Kaplan-Meier-based meta-analysis and 33 studies (16 933 patients) in an aggregate data meta-analysis. In the Kaplan-Meier-based analysis, the median survival time for patients surviving to hospital discharge was 5.0 years (IQR, 2.3-7.9 years). The estimated survival rates were 82.8% (95% CI, 81.9%-83.7%) at 3 years, 77.0% (95% CI, 75.9%-78.0%) at 5 years, 63.9% (95% CI, 62.3%-65.4%) at 10 years, and 57.5% (95% CI, 54.8%-60.1%) at 15 years. Compared with patients with a nonshockable initial rhythm, patients with a shockable rhythm had a lower risk of long-term mortality (hazard ratio, 0.30; 95% CI, 0.23-0.39; P < .001). Different analyses, including an aggregate data meta-analysis, confirmed these results. Conclusions and Relevance: In this comprehensive systematic review and meta-analysis, long-term survival after 10 years in patients surviving the initial hospital stay after OHCA was between 62% and 64%. Additional research is needed to understand and improve the long-term survival in this vulnerable patient population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.