Evidence map›Paper›PMID 35507254›Full record

ReviewCardiovascular toxicology2022

Evaluating the Role of lncRNAs in the Incidence of Cardiovascular Diseases in Androgenetic Alopecia Patients.

Masoumeh Roohaninasab, Shadnaz Fakhteh Yavari, Motahareh Babazadeh, Rozita Adldoosti Hagh, Mahboubeh Pazoki, Mehran Amrovani

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cardiovascular toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Masoumeh RoohaninasabDepartment of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences, Sattarkhan St, Tehran, 1445613131, Iran.
Shadnaz Fakhteh YavariDepartment of Tissue Engineering and Applied Cell Science, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
Motahareh BabazadehDepartment of Dermatology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Rozita Adldoosti HaghArdabil University of Medical Science, Ardabil, Iran.
Mahboubeh PazokiDepartment of Cardiology, Rasoul Akram General Hospital, Iran University of Medical Sciences, Tehran, Iran. mahpazoki87@gmail.com.
Mehran AmrovaniHigh Institute for Education and Research in Transfusion Medicine, Tehran, Iran. e.amrovani@gmail.com.
Iran University of Medical Sciences · IRAhvaz Jundishapur University of Medical Sciences · IRArdabil University of Medical Sciences · IRHigh Institute for Education and Research in Transfusion Medicine · IRShahid Beheshti University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hair loss occurs in patients with Androgenetic Alopecia (AGA). The pattern of hair loss is different between men and women. The main cause of hair loss is increased cell apoptosis and decreased regeneration, proliferation and differentiation processes in hair follicles. Long Non-Coding RNAs (lncRNAs) are one of the most important molecules that regulate the processes of apoptosis, regeneration, proliferation and differentiation in hair follicles. Since studies have shown that lncRNAs can be effective in the development of cardiotoxicity and induction of cardiovascular disease (CVD); so effective lncRNAs in the regulation of regeneration, proliferation, differentiation and apoptosis of hair follicles can be involved in the development of CVD in AGA patients with. Therefore, this study investigated the lncRNAs involved in increasing apoptosis and reducing the processes of regeneration, proliferation and differentiation of hair follicles. The aim of the current study was to evaluate the role of lncRNAs as a risk factor in the incidence of CVD in AGA patients; it will help to design treatment strategies by targeting signaling pathways without any cardiotoxicity complications.

Indexed as

Cardiovascular DiseasesRNA, Long NoncodingAlopeciaCardiotoxicityFemaleHumansIncidenceMaleRNA, Long NoncodingAlopecia AndrogeneticCardiovascular diseaseLong non-coding RNAPathogenesis

Identifiers

PMID35507254
OpenAlexW4225427560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.