Observational studyRheumatology international2022
Shear wave elastography as a potential additional diagnostic tool in primary Sjögren's syndrome: an observational study.
Observational study in Rheumatology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Pooled it
- Does ultrasound elastography have a role as a diagnostic method for Sjögren's syndrome in the salivary glands? A systematic review.Oral radiology · 2024Pooled it
- The diagnostic performance of salivary gland ultrasound elastography in Sjögren's syndrome and sicca symptoms: a systematic review and meta-analysis.European radiology · 2024Pooled it
- Investigation of the effect of different intensity stabilization exercises on core muscle stiffness and pain in chronic low back pain: a single-blind, randomized controlled trial.Rheumatology international · 2025Trial
- Assessment of salivary gland involvement in primary Sjögren's syndrome using ultrasound viscoelasticity imaging.European radiology · 2026Article
- Ultrasonographic Evaluation of Salivary Gland Stiffness in Primary Sjögren's Disease and Idiopathic Xerostomia.Oral diseases · 2026Article
- Increased thyroid stiffness without volume change in systemic sclerosis: a case-control study using two-dimensional shear wave elastography.Rheumatology international · 2026Article
- Diagnostic performance of conventional ultrasound and shear wave elastography of the parotid glands in primary Sjögren's syndrome.BMC medical imaging · 2026Article
- Value of combined application of the OMERACT scoring system and shear wave elastography for primary Sjögren's syndrome.Clinical rheumatology · 2025Article
- Ultrasound shear wave elastography for assessing minor salivary gland involvement in anti-centromere antibody-positive primary Sjögren's syndrome: a retrospective study.Clinical and experimental medicine · 2024Review
- Performance of salivary glands ultrasonography, shear wave elastography and their combined use for the diagnosis of primary and secondary Sjögren's syndrome.Journal of applied clinical medical physics · 2024Article
- Assessment of lacrimal gland involvement in primary Sjögren's syndrome using gray-scale ultrasonography and shear wave elastography.European radiology · 2023Article
- The use of shear wave elastography to monitor changes in gingival elasticity associated with initial periodontal therapy in patients with advanced periodontitis: A prospective pilot study.Journal of dental sciences · 2023Article
- A few considerations on strain sonoelastographic measurements of quadriceps and patellar tendons in knee osteoarthritis.Rheumatology international · 2023Article
- Effectiveness of shear wave elastography for assessing major salivary gland involvement in ankylosing spondylitis.Radiologia brasileiraArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The primary aim of this study was to verify if shear wave elastography can be used to evaluate salivary gland involvement in primary Sjögren's syndrome (pSS). The secondary objective was to establish an accurate cut-off value for parotid and submandibular salivary gland stiffness and to verify whether there are any distinctions among pSS patients with or without subjective mouth dryness. This prospective study included 45 patients with pSS (2016 ACR/EULAR classification criteria) and 108 healthy controls. All subjects underwent bilateral shear wave elastography of the parotid and submandibular salivary glands. Clinical data of pSS patients were collected and compared to elastography results. Patients with pSS had significantly higher shear wave elastography values for the parotid and submandibular salivary glands than the controls. There were no statistical differences in SWE values between patients with or without mouth dryness. The optimal cut-off value (mean value of 4 salivary glands shear wave elastography results) to distinguish patients with or without pSS was 13.19 kPa with sensitivity = 97.8% and specificity = 100.0%. It was, therefore, confirmed that shear wave elastography measurement of salivary glands has strong predictive ability in pSS detection (AUC 97.8%, 95% CI 93.4-100.0%). Shear wave elastography seems to be a promising, non-invasive and simple quantitative adjunct test to support the diagnosis of pSS with good sensitivity and specificity. More extensive prospective studies are needed to standardize a study protocol.
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