Evidence map›Paper›PMID 35507059›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Deep learning-based time-of-flight (ToF) image enhancement of non-ToF PET scans.

Abolfazl Mehranian, Scott D Wollenweber, Matthew D Walker, Kevin M Bradley, Patrick A Fielding, Martin Huellner, Fotis Kotasidis, Kuan-Hao Su, Robert Johnsen, Floris P Jansen and 1 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  15. Deep Convolutional Backbone Comparison for Automated PET Image Quality Assessment.IEEE transactions on radiation and plasma medical sciences · 2024
    Article
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  17. Influence of Covariates onDiagnostics (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abolfazl MehranianGE Healthcare, Big Data Institute, University of Oxford, Oxford, UK.
Scott D WollenweberGE Healthcare, Waukesha, WI, USA.
Matthew D WalkerDepartment of Medical Physics and Clinical Engineering, Oxford University Hospitals NHS FT, Oxford, UK.
Kevin M BradleyWales Research and Diagnostic PET Imaging Centre, University Hospital of Wales, Cardiff, UK.
Patrick A FieldingDepartment of Radiology, University Hospital of Wales, Cardiff, UK.
Martin HuellnerZurich University Hospital, Zurich, Switzerland.
Fotis KotasidisGE Healthcare, Zurich, Switzerland.
Kuan-Hao SuGE Healthcare, Waukesha, WI, USA.
Robert JohnsenGE Healthcare, Waukesha, WI, USA.
Floris P JansenGE Healthcare, Waukesha, WI, USA.
Daniel R McGowanDepartment of Medical Physics and Clinical Engineering, Oxford University Hospitals NHS FT, Oxford, UK. Daniel.McGowan@oncology.ox.ac.uk.ORCID 0000-0002-6880-5687

Funding

Cancer Research UK 28684
6 · The paper itself

Abstract

purposeTo improve the quantitative accuracy and diagnostic confidence of PET images reconstructed without time-of-flight (ToF) using deep learning models trained for ToF image enhancement (DL-ToF).

methodsA total of 273 [

resultsThe non-ToF, DL-ToF low, medium, and high methods resulted in - 28 ± 18, - 28 ± 19, - 8 ± 22, and 1.7 ± 24% differences (mean; SD) in the SUV

conclusionDeep learning-based image enhancement models may provide converged ToF-equivalent image quality without ToF reconstruction. In clinical scoring DL-ToF-enhanced non-ToF images (medium and high) on average scored as high as, or higher than, ToF images. The model is generalisable and hence, could be applied to non-ToF images from BGO-based PET/CT scanners.

Indexed as

Deep LearningPositron Emission Tomography Computed TomographyAlgorithmsFluorodeoxyglucose F18HumansImage Processing, Computer-AssistedPositron-Emission TomographyTomography, X-Ray ComputedFluorodeoxyglucose F18Deep neural networksImage qualityPETTime of flight

Identifiers

PMID35507059
PMCPMC9399038

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.