Evidence map›Paper›PMID 35506630›Full record

ArticleMolecular omics2022

Changes in lipid profile and SOX-2 expression in RM-1 cells after co-culture with preimplantation embryos or with deproteinated blastocyst extracts.

Nicolás M Morato, Judy E Hallett, Wen-Hung Wang, Bennett D Elzey, Gregory M Cresswell, Bruce R Cooper, Christina R Ferreira

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular omics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nicolás M MoratoDepartment of Chemistry and Center for Analytical Instrumentation Development, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0003-0218-407X
Judy E HallettTransgenic and Genome Editing Facility, Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, USA.
Wen-Hung WangGene Editing Core, Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, USA.
Bennett D ElzeyDepartment of Comparative Pathology, Purdue University, West Lafayette, IN 47907, USA.
Gregory M CresswellDepartment of Comparative Pathology, Purdue University, West Lafayette, IN 47907, USA.
Bruce R CooperMetabolite Profiling Facility, Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, USA. cferrei@purdue.edu.
Christina R FerreiraMetabolite Profiling Facility, Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, USA. cferrei@purdue.edu.ORCID 0000-0003-3988-6454
Purdue University West Lafayette · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI Andrea L Kasinski · 1985 to 2026
$43.4M
Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
NCATS NIH HHS UL1 TR002529NCI NIH HHS P30 CA023168
6 · The paper itself

Abstract

The embryonic environment can modify cancer cell metabolism, and it is reported to induce the loss of tumorigenic properties and even affect the differentiation of cancer cells into normal tissues. The cellular mechanisms related to this remarkable phenomenon, which is likely mediated by cell-to-cell communication, have been previously investigated with particular focus on the proteins and genes involved. In this study we report the optimization and results of a straightforward

Indexed as

BlastocystEmbryonic DevelopmentAnimalsCoculture TechniquesLipidsMaleMiceLipids

Identifiers

PMID35506630
PMCPMC9276632
OpenAlexW4225692072

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.