Evidence map›Paper›PMID 35506369›Full record

ArticleJournal of medical radiation sciences2022

Not all 3D-printed bolus is created equal: Variation between 3D-printed polylactic acid (PLA) bolus samples sourced from external manufacturers.

Kerryn Brown, Tom Kupfer, Benjamin Harris, Sam Penso, Richard Khor, Eka Moseshvili

Abstract read
In one paragraph

Article in Journal of medical radiation sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kerryn BrownDepartment of Radiation Oncology, ONJ Centre, Austin Hospital, Heidelberg, Australia.ORCID https://orcid.org/0000-0001-8321-815X
Tom KupferDepartment of Radiation Oncology, ONJ Centre, Austin Hospital, Heidelberg, Australia.
Benjamin HarrisDepartment of Radiation Oncology, ONJ Centre, Austin Hospital, Heidelberg, Australia.
Sam PensoDepartment of Radiation Oncology, ONJ Centre, Austin Hospital, Heidelberg, Australia.
Richard KhorDepartment of Radiation Oncology, ONJ Centre, Austin Hospital, Heidelberg, Australia.ORCID https://orcid.org/0000-0002-7057-2747
Eka MoseshviliDepartment of Radiation Oncology, ONJ Centre, Austin Hospital, Heidelberg, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPolylactic acid (PLA) is a promising material for customised bolus 3D-printing in radiotherapy, however variations in printing techniques between external manufacturers could increase treatment uncertainties. This study aimed to assess consistency across various 3D-printed PLA samples from different manufacturers.

methodsSample prints of dimensions 5 × 5 × 1 cm with 100% infill were acquired from multiple commercial 3D-printing services. All samples were CT scanned to determine average Hounsfield unit (HU) values and physical densities. The coefficient of equivalent thickness (CET) was obtained for both photons and electrons and dose attenuation compared to TPS calculations in Elekta Monaco v5.11.

resultsSome samples showed warped edges up to 1.5 mm and extensive internal radiological defects only detectable with CT scanning. Physical densities ranged from 1.06 to 1.22 g cm

conclusions3D-printed PLA can have considerable variability in density, HU and CET values between samples and manufacturers. Centres looking to outsource 3D-printed bolus would benefit from clear, open communication with manufacturers and undertake stringent QA examination prior to implementation into the clinical environment.

Indexed as

PolyestersPrinting, Three-DimensionalPhantoms, ImagingTomography, X-Ray ComputedPolyesterspoly(lactide)3D-printingbolusPLApolylactic acidradiotherapy

Identifiers

PMID35506369
PMCPMC9442296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.