Evidence map›Paper›PMID 35506246›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2022

Neighborhood Obesogenic Environment and Risk of Prostate Cancer: The Multiethnic Cohort.

Mindy C DeRouen, Li Tao, Salma Shariff-Marco, Juan Yang, Yurii B Shvetsov, Song-Yi Park, Cheryl L Albright, Kristine R Monroe, Loïc Le Marchand, Lynne R Wilkens and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Breast, Colorectal, and Prostate Cancer Incidence among Filipino Americans by Generational Status in the Multiethnic Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Mindy C DeRouenDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.ORCID 0000-0002-7198-7629
Li TaoDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Salma Shariff-MarcoDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Juan YangDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Yurii B ShvetsovEpidemiology Program, University of Hawai'i Cancer Center, Honolulu, Hawaii.ORCID 0000-0001-5131-9618
Song-Yi ParkEpidemiology Program, University of Hawai'i Cancer Center, Honolulu, Hawaii.ORCID 0000-0001-7734-5320
Cheryl L AlbrightNancy Atmospera-Walch School of Nursing, Honolulu, Hawaii.ORCID 0000-0003-4569-0407
Kristine R MonroeUniversity of Southern California, Los Angeles, California.ORCID 0000-0002-3016-2081
Loïc Le MarchandEpidemiology Program, University of Hawai'i Cancer Center, Honolulu, Hawaii.
Lynne R WilkensEpidemiology Program, University of Hawai'i Cancer Center, Honolulu, Hawaii.
Scarlett Lin GomezDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Iona ChengDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
University of California, San Francisco · USCancer Center of Hawaii · USUniversity of Southern California · USWorld Medicine Institute · US

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GERTRAUD MASKARINEC · 1996 to 2026
$56.2M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
Obesogenic environment: impact on breast, colorectal, and prostate cancer riskR01CA154644 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI CHENG, IONA C · 2011 to 2015
$1.4M
Social and built environment and race/ethnic variations in cancer outcomesR03CA117324 · NCI · CANCER PREVENTION INSTIT OF CALIFORNIA · PI GOMEZ, SCARLETT L · 2006 to 2007
$139k
NCI NIH HHS N01 PC035136NCI NIH HHS P30 CA071789NCI NIH HHS R01 CA154644NCI NIH HHS R03 CA117324NCI NIH HHS U01 CA164973
6 · The paper itself

Abstract

backgroundObesity is associated with risk of aggressive prostate cancer. It is not known whether neighborhood obesogenic factors are independently associated with prostate cancer risk.

methodsNeighborhood socioeconomic status (nSES) and four neighborhood obesogenic environment factors (urbanicity, mixed-land development, unhealthy food environment, and parks) were assessed for associations with prostate cancer risk among 41,563 African American, Japanese American, Latino, and White males in the Multiethnic Cohort (MEC) Study, California site. Multivariable Cox proportional hazards regression was used to estimate HRs and 95% confidence intervals (CI) for nonaggressive and aggressive prostate cancer, adjusting for individual-level sociodemographic, behavioral, and prostate cancer risk factors. Analyses were stratified by race, ethnicity, and, among Latino males, nativity.

resultsMales residing in low-SES, compared with high-SES, neighborhoods had lower risk of nonaggressive prostate cancer [lowest vs. highest quintile HR = 0.81; 95% confidence interval (CI) = 0.68-0.95, Ptrend 0.024], driven by a similar trend among foreign-born Latino males. Foreign-born Latino males in neighborhoods with low mixed-land development had increased risk of non-aggressive disease (lowest vs. highest quintile HR = 1.49; 95% CI = 1.07-2.09). For aggressive disease, the only association noted was between lower mixed-land development and lower risk among White males (Ptrend = 0.040).

conclusionsnSES and obesogenic environment factors were independently associated with prostate cancer risk; associations varied by race, ethnicity, nativity, and disease aggressiveness. IMPACT: Upstream structural and social determinants of health that contribute to neighborhood obesogenic characteristics likely impact prostate cancer risk differently across groups defined by race, ethnicity, and nativity and by disease aggressiveness.

Indexed as

Prostatic NeoplasmsResidence CharacteristicsCohort StudiesHispanic or LatinoHumansMaleSocial Class

Identifiers

PMID35506246
PMCPMC9074096
OpenAlexW4225400065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.