Evidence map›Paper›PMID 35506132›Full record

ArticleRadiology. Cardiothoracic imaging2022

MRI Phase-Contrast Blood Flow in Fasting Pediatric Patients with Fontan Circulation Correlates with Exercise Capacity.

Christopher Z Lam, Dawn David, Laura Acosta Izquierdo, Parneyan Pezeshkpour, Anne I Dipchand, Emilie Jean-St-Michel, Rajiv R Chaturvedi, Simon C Ling, Rachel M Wald, Govind B Chavhan and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Radiology. Cardiothoracic imaging · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Christopher Z LamDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).ORCID https://orcid.org/0000-0002-4605-5600
Dawn DavidDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).ORCID 0000-0001-5389-6646
Laura Acosta IzquierdoDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).ORCID 0000-0003-4346-297X
Parneyan PezeshkpourDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).
Anne I DipchandDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).ORCID 0000-0001-6323-7222
Emilie Jean-St-MichelDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).
Rajiv R ChaturvediDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).ORCID 0000-0002-4474-7304
Simon C LingDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).ORCID 0000-0002-4223-4601
Rachel M WaldDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).ORCID 0000-0002-2373-6438
Govind B ChavhanDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).ORCID 0000-0003-1111-2457
Michael SeedDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).
Shi-Joon YooDepartment of Diagnostic Imaging (C.Z.L., D.D., L.A.I., P.P., G.B.C., M.S., S.J.Y.), Division of Cardiology, Department of Paediatrics (A.I.D., E.J.S.M., R.R.C., R.M.W., M.S., S.J.Y.), and Division of Gastroenterology, Department of Paediatrics (S.C.L.), Hospital for Sick Children, University of Toronto, 555 University Ave, Toronto, ON, Canada M5G 1X8; Department of Medical Imaging, University of Toronto, Toronto, Canada (C.Z.L., L.A.I., G.B.C., S.J.Y.); Joint Department of Medical Imaging, University Health Network, Toronto, Canada (R.M.W.); and Peter Munk Cardiac Centre, University Health Network, Toronto General Hospital, Toronto, Canada (R.M.W.).ORCID https://orcid.org/0000-0002-9952-8504

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To assess regional blood flow in fasting pediatric patients with Fontan circulation by using MRI and to explore associations with clinical parameters. Materials and Methods: In this retrospective study, pediatric patients who had undergone the Fontan procedure (<18 years of age) and had undergone clinical cardiac MRI, performed after at least 4 hours of fasting, between 2018 and 2021 were included. Regional blood flow was compared with published healthy volunteer data ( Results: Fifty-five patients (38 boys) with median age at MRI of 14 years (IQR, 11-16 years) and median time from Fontan procedure to MRI of 10 years (IQR, 8-12 years) were included. Patients after Fontan procedure had lower ascending aortic, inferior vena cava, and total systemic blood flow compared with healthy volunteers (3.00 L/min/m Conclusion: Reference ranges are provided for regional systemic blood flow derived by using MRI in fasting pediatric patients with Fontan circulation, who had lower systemic blood flow compared with healthy volunteers. Lower fasting Fontan blood flow correlated with lower exercise capacity.

Indexed as

CardiacCongenitalHeartHemodynamics/Flow DynamicsMR ImagingPediatrics

Identifiers

PMID35506132
PMCPMC9059244

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.