Evidence map›Paper›PMID 35506114›Full record

ArticlePulmonary circulation2022

Predicting pulmonary embolism among hospitalized patients with machine learning algorithms.

Logan Ryan, Jenish Maharjan, Samson Mataraso, Gina Barnes, Jana Hoffman, Qingqing Mao, Jacob Calvert, Ritankar Das

Abstract read
In one paragraph

Article in Pulmonary circulation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  14. Availability in ECMO Reduces the Failure to Rescue in Patients With Pulmonary Embolism After Major Surgery: A Nationwide Analysis of 2.4 Million Cases.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Logan RyanDascena, Inc. Houston Texas USA.
Jenish MaharjanDascena, Inc. Houston Texas USA.
Samson MatarasoDascena, Inc. Houston Texas USA.
Gina BarnesDascena, Inc. Houston Texas USA.ORCID 0000-0002-8093-0245
Jana HoffmanDascena, Inc. Houston Texas USA.
Qingqing MaoDascena, Inc. Houston Texas USA.
Jacob CalvertDascena, Inc. Houston Texas USA.
Ritankar DasDascena, Inc. Houston Texas USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary embolisms (PE) are life-threatening medical events, and early identification of patients experiencing a PE is essential to optimizing patient outcomes. Current tools for risk stratification of PE patients are limited and unable to predict PE events before their occurrence. Objective: We developed a machine learning algorithm (MLA) designed to identify patients at risk of PE before the clinical detection of onset in an inpatient population. Materials and Methods: Three machine learning (ML) models were developed on electronic health record data from 63,798 medical and surgical inpatients in a large US medical center. These models included logistic regression, neural network, and gradient boosted tree (XGBoost) models. All models used only routinely collected demographic, clinical, and laboratory information as inputs. All were evaluated for their ability to predict PE at the first time patient vital signs and lab measures required for the MLA to run were available. Performance was assessed with regard to the area under the receiver operating characteristic (AUROC), sensitivity, and specificity. Results: The model trained using XGBoost demonstrated the strongest performance for predicting PEs. The XGBoost model obtained an AUROC of 0.85, a sensitivity of 81%, and a specificity of 70%. The neural network and logistic regression models obtained AUROCs of 0.74 and 0.67, sensitivity of 81% and 81%, and specificity of 44% and 35%, respectively. Conclusions: This algorithm may improve patient outcomes through earlier recognition and prediction of PE, enabling earlier diagnosis and treatment of PE.

Indexed as

anticoagulantsartificial intelligenceclinicaldecision support systemsthrombosis

Identifiers

PMID35506114
PMCPMC9052977

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.