Evidence map›Paper›PMID 35506112›Full record

ArticlePulmonary circulation2022

Disease characteristics and clinical outcome over two decades from the Swiss pulmonary hypertension registry.

Paula Appenzeller, Mona Lichtblau, Charlotte Berlier, John-David Aubert, Andrea Azzola, Jean-Marc Fellrath, Thomas Geiser, Frederic Lador, Susanne Pohle, Isabelle Opitz and 5 more

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Paula AppenzellerClinic of Pulmonology, University Hospital Zurich Zurich Switzerland.
Mona LichtblauClinic of Pulmonology, University Hospital Zurich Zurich Switzerland.ORCID https://orcid.org/0000-0003-4485-1758
Charlotte BerlierClinic of Pulmonology, University Hospital Zurich Zurich Switzerland.
John-David AubertCenter of Pulmonology, CHUV Lausanne Switzerland.
Andrea AzzolaCenter of Pulmonology, Cantonal Hospital Lucerne Lucerne Switzerland.
Jean-Marc FellrathCenter of Pulmonology, Hôpital neuchâtelois Pourtalès Neuenburg Switzerland.
Thomas GeiserInterdisciplinary Center for Pulmonary Hypertension, Bern University Hospital and University of Bern Bern Switzerland.
Frederic LadorPulmonary Hypertension Program, University Hospital of Geneva Geneva Switzerland.
Susanne PohleLung Center, Cantonal Hospital St. Gallen St. Gallen Switzerland.
Isabelle OpitzDepartment of Thoracic Surgery University Hospital Zurich Zurich Switzerland.
Markus SchwerzmannInterdisciplinary Center for Pulmonary Hypertension, Bern University Hospital and University of Bern Bern Switzerland.
Hans StrickerDepartment of Angiology Ospedale La Carità Locarno Switzerland.
Michael TammCenter of Pulmonology, University Hospital Basel Basel Switzerland.
Stéphanie SaxerClinic of Pulmonology, University Hospital Zurich Zurich Switzerland.ORCID https://orcid.org/0000-0002-3278-6277
Silvia UlrichClinic of Pulmonology, University Hospital Zurich Zurich Switzerland.ORCID https://orcid.org/0000-0002-5250-5022
University Hospital of Zurich · CHUniversity of Bern · CHHôpital Orthopédique de la Suisse Romande · CHHospital Neuchâtel · CHOspedale Regionale di Locarno · CHUniversity Hospital of Basel · CHUniversity Hospital of Geneva · CHUniversity of Lucerne · CHUniversity of St.Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension (PH), especially pulmonary arterial and chronic thromboembolic pulmonary hypertension (PAH/CTEPH), are rare and progressive conditions. Despite recent advances in treatment and prognosis, PH is still associated with impaired quality of life and survival. Long-term PH-registry data provide information on the changing PH-epidemiology and may help to direct resources to patient's needs. This retrospective analysis of the Swiss Pulmonary Hypertension Registry includes patients newly diagnosed with PH (mainly PAH/CTEPH) registered from January 2001 to June 2019 at 13 Swiss hospitals. Patient characteristics (age, body mass index, gender, diagnosis), hemodynamics at baseline, treatment, days of follow-up, and events (death, transplantation, pulmonary endarterectomy, or loss to follow-up) at last visit were analyzed. Patients were stratified into four time periods according to their date of diagnosis. Survival was analyzed overall and separately for PAH/CTEPH and time periods. 1427 PH patients were included (thereof 560 PAH, 383 CTEPH). Over the years, age at baseline (mean ± SD) significantly increased from 59 ± 14 years in 2001-2005 to 66 ± 14 years in 2016-2019 (

Indexed as

chronic thromboembolic pulmonary hypertensionpulmonary arterial hypertensionsurvival

Identifiers

PMID35506112
PMCPMC9052988
OpenAlexW4200622415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.