Evidence map›Paper›PMID 35506092›Full record

ReviewPulmonary circulation2022

Respiratory system as the main determinant of dyspnea in patients with pulmonary hypertension.

Ioanna Mitrouska, Maria Bolaki, Katerina Vaporidi, Dimitris Georgopoulos

Open access · goldAbstract readReview
In one paragraph

Review in Pulmonary circulation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. [The lungs: starting point for many diseases].Innere Medizin (Heidelberg, Germany) · 2023
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ioanna MitrouskaDepartment of Pulmonary Medicine, University Hospital of Heraklion, Medical School University of Crete Heraklion Crete Greece.
Maria BolakiDepartment of Intensive Care Medicine, University Hospital of Heraklion, Medical School University of Crete Heraklion Crete Greece.
Katerina VaporidiDepartment of Intensive Care Medicine, University Hospital of Heraklion, Medical School University of Crete Heraklion Crete Greece.
Dimitris GeorgopoulosDepartment of Intensive Care Medicine, University Hospital of Heraklion, Medical School University of Crete Heraklion Crete Greece.ORCID 0000-0003-3689-9014
University of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dyspnea on exertion is a devastating symptom, commonly observed in patients with pulmonary hypertension (PH). The pathophysiology of dyspnea in these patients has been mainly attributed to cardiovascular determinants and isolated abnormalities of the respiratory system during exercise, neglecting the contribution of the control of the breathing system. The aim of this review is to provide a novel approach to the interpretation of dyspnea in patients with PH, focused on the impact of the control of the breathing system during exercise. Exercise through multiple mechanisms affects the (1) ventilatory demands, as dictated by respiratory center activity, (2) actual ventilation, and (3) metabolic hyperbola. In patients with PH, exertional dyspnea can be explained by exercise-induced alterations in these variables. Compared to healthy subjects, at a given CO

Indexed as

brain curveexercisemetabolic hyperbolaventilation curve

Identifiers

PMID35506092
PMCPMC9053013
OpenAlexW4220957241

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.