Evidence map›Paper›PMID 35506088›Full record

ArticlePulmonary circulation2022

Retinal vessel changes in pulmonary arterial hypertension.

Mariana DuPont, Savanna Lambert, Antonio Rodriguez-Martin, Okaeri Hernandez, Mark Lagatuz, Taygan Yilmaz, Andrew Foderaro, Grayson L Baird, Patricia Parsons-Wingerter, Tim Lahm and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Mariana DuPontDepartment of Ophthalmology and Visual Sciences University of Alabama at Birmingham Birmingham Alabama USA.ORCID 0000-0001-7986-3383
Savanna LambertSchool of Public Health University of Alabama Birmingham Birmingham Alabama USA.
Antonio Rodriguez-MartinDepartment of Clinical & Diagnostic Sciences University of Alabama at Birmingham Birmingham Alabama USA.
Okaeri HernandezDepartment of Biology University of Alabama at Birmingham Birmingham Alabama USA.
Mark LagatuzRedline Performance Solutions, Ames Research Center National Aeronautics and Space Administration Moffett Field California USA.
Taygan YilmazDivision of Ophthalmology and Department of Surgery Alpert Medical School of Brown University Providence Rhode Island USA.
Andrew FoderaroDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine Alpert Medical School of Brown University Providence Rhode Island USA.
Grayson L BairdDepartment of Diagnostic Imaging, Alpert Medical School of Brown University Rhode Island Hospital Providence Rhode Island USA.
Patricia Parsons-WingerterLow Gravity Exploration Technology, Research, and Engineering Directorate, John Glenn Research Center National Aeronautics and Space Administration Cleveland Ohio USA.
Tim LahmDepartment of Medicine, Division of Pulmonary Critical Care, Occupational and Sleep Medicine Indiana University Indianapolis Indiana USA.
Maria B GrantDepartment of Ophthalmology and Visual Sciences University of Alabama at Birmingham Birmingham Alabama USA.
Corey E VentetuoloDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine Alpert Medical School of Brown University Providence Rhode Island USA.ORCID 0000-0002-4223-4775
Brown University · USUniversity of Alabama at Birmingham · USAmes Research Center · USGlenn Research Center · US

Funding

Visual Phenotyping CoreP30EY003039 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul Douglas Gamlin · 1985 to 2026
$16.9M
NITRIC OXIDE IN THE PATHOGENESIS OF DIABETIC RETINOPATHYR01EY012601 · NEI · UNIVERSITY OF FLORIDA · PI Julia V Busik, Maria Bartolomeo Grant · 1998 to 2026
$9.6M
Mechanisms of Right Ventricle Adaptation to Pulmonary HypertensionR01HL144727 · NHLBI · NATIONAL JEWISH HEALTH · PI Tim Lahm · 2019 to 2026
$4.7M
Effects of DHEA in Pulmonary Hypertension (DiPH)R01HL141268 · NHLBI · RHODE ISLAND HOSPITAL · PI VENTETUOLO, COREY E · 2018 to 2022
$3.7M
ACE2 Modulates the Bone Marrow- Gut Axis in Diabetic RetinopathyR01EY028858 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BOULTON, MICHAEL EDWIN, GRANT, MARIA BARTOLOMEO · 2018 to 2021
$1.6M
A critical role for intracellular VEGF receptor translocation in ocular angiogenesisR01EY028861 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BOULTON, MICHAEL EDWIN, GRANT, MARIA BARTOLOMEO · 2018 to 2021
$1.5M
BLRD VA I01 BX002042NEI NIH HHS P30 EY003039NEI NIH HHS R01 EY012601NEI NIH HHS R01 EY028858NEI NIH HHS R01 EY028861NHLBI NIH HHS R01 HL141268NHLBI NIH HHS R01 HL144727
6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) is classically considered an isolated small vessel vasculopathy of the lungs with peripheral pulmonary vascular obliteration. Systemic manifestations of PAH are increasingly acknowledged, but data remain limited. We hypothesized that retinal vascular changes occur in PAH. PAH subjects underwent retinal fluorescein angiography (FA) and routine disease severity measures were collected from the medical record. FA studies were analyzed using VESsel GENerational Analysis (VESGEN), a noninvasive, user-interactive computer software that assigns branching generation to large and small vessels. FAs from controls (

Indexed as

hemodynamicsmicrovascularpulmonary vascular diseaseretinaVESGEN

Identifiers

PMID35506088
PMCPMC9052984
OpenAlexW4212834239

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.