Evidence map›Paper›PMID 35506008›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering

Monte Carlo simulation of Cherenkov imaging for Total Skin Electron Treatment with CT DICOM realistic patient geometry.

Weili Zhong, Yihong Ong, Tianshu Miao, Brian W Pogue, Timothy C Zhu

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Stereo Cherenkov imaging as 3D absolute dose monitoring tool for total skin electron therapy (TSET).Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
  2. Assessment of generic corrections for multiview Cherenkov emission during total skin electron therapy (TSET).Proceedings of SPIE--the International Society for Optical Engineering · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Weili ZhongPerelman School of Medicine, University of Pennsylvania, Philadelphia, USA, PA 19104.
Yihong OngPerelman School of Medicine, University of Pennsylvania, Philadelphia, USA, PA 19104.
Tianshu MiaoYale School of Medicine, Yale University, New Haven, CT USA, 06520.
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, NH USA, 03755.
Timothy C ZhuPerelman School of Medicine, University of Pennsylvania, Philadelphia, USA, PA 19104.
California University of Pennsylvania · USDartmouth College · USYale University · US

Funding

Cherenkov imaging of Total Skin Electron Therapy (TSET)R21CA239127 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ZHU, TIMOTHY C. · 2020 to 2021
$386k
NCI NIH HHS R21 CA239127
6 · The paper itself

Abstract

This Monte Carlo (MC) simulation study provides an evaluation of dose uniformity in a patient and the difference between dose and Cherenkov distributions, which is invaluable in developing conversion factors to relate observed Cherenkov images to actual dose distributions for TSET patients. This MC simulations with TOPAS is performed using realistic patient geometries obtained with a 3D scanner during total skin electron treatments (TSET) at UPenn. For each treatment posture in the Stanford technique, the differences between Cherenkov photon distributions and dose distributions produced in MC are consistent with the differences observed between a Cherenkov imaging camera and in-vivo dose measurement with OSLD on patient skin. According to MC studies of a flat rectangular PVC board, the difference between Cherenkov and dose is mostly due to the spoiler. This is confirmed by observing consistent dose and Cherenkov distributions in clinical measurements on a PVC board without the spoiler. The accumulated dose and Cherenkov distributions for each patient are obtained by projecting the MC output of the 6 postures of the TSET treatment together onto a finite element model of the patient.

Indexed as

Cherenkov imagingCT DICOMMonte Carlo simulationTOPAStotal skin electron treatment

Identifiers

PMID35506008
PMCPMC9060570
OpenAlexW4220660716

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.