Evidence map›Paper›PMID 35505857›Full record

ArticlePolish journal of radiology2022

Study of renal parenchymal changes by diffusion tensor imaging in diabetic nephropathy.

Anish Haladi Panduranga, Kirti Chaturvedy, Manish Chaturvedy, Prateek Sihag, Girja Nandvanshi, Sunil Vishnoi, Abhishek Kaushik, Asaf Ali Khammar

Open access · diamondAbstract read
In one paragraph

Article in Polish journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anish Haladi PandurangaDepartment of Radiodiagnosis, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India.
Kirti ChaturvedyDepartment of Radiodiagnosis, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India.
Manish ChaturvedyDepartment of Nephrology, AIIMS Jodhpur, Rajasthan, India.
Prateek SihagAIIMS Bilaspur, Himachal Pradesh, India.
Girja NandvanshiDepartment of Radiodiagnosis, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India.
Sunil VishnoiDepartment of Radiodiagnosis, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India.
Abhishek KaushikDepartment of Radiodiagnosis, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India.
Asaf Ali KhammarDepartment of Radiodiagnosis, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India.
All India Institute of Medical Sciences · INAll India Institute of Medical Sciences Bhopal · INAll India Institute of Medical Sciences Jodhpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate differences in diffusion imaging parameters, including fractional anisotropy (FA) and the apparent diffusion coefficient (ADC), in control and diabetic subjects, and to assess changes in these parameters to patient's urine albumin/protein levels, estimated glomerular filtration rate (eGFR), and glycated haemoglobin (HbA Material and methods: This is a cross-sectional analytical study involving 100 patients who underwent diffusion imaging including diffusion tensor imaging (DTI) of the kidneys in our hospital from 2019 to 2020. Diffusion imaging parameters (ADC and FA) were obtained from the medulla and cortex of both kidneys using dedicated software. Statistical analysis was done. Results: Out of 100 subjects, 27 were controls and 73 were diabetics (19 normoalbuminuric, 23 microalbuminuric, and 31 proteinuric). The medullary FA (0.419 ± 0.024 vs. 0.346 ± 0.042), cortical FA (0.194 ± 0.035 vs. 0.303 ± 0.067), and cortical ADC (3.307 ± 0.341 vs. 2.309 ± 0.515) values showed significant differences between controls and diabetics. Medullary FA and cortical ADC values showed a decreasing trend with an increasing amount of albumin/protein in the urine, decreasing renal function (reducing eGFR), and increasing HbA Conclusions: DTI has the potential to be a promising non-invasive test for the detection of early renal parenchymal changes in diabetic nephropathy.

Indexed as

ADCdiabetic nephropathydiffusion tensor imagingDTIFArenal DTI

Identifiers

PMID35505857
PMCPMC9047783
OpenAlexW4226391377

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.