ArticleJournal of inflammation research2022
Elevated Albumin to Globulin Ratio on Day 7 is Associated with Improved Function Outcomes in Acute Ischemic Stroke Patients with Intravenous Thrombolysis.
Article in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Serum Albumin and Post-Stroke Outcomes: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis.Nutrients · 2024Pooled it
- Integrating serum globulin into the ICF framework: a novel multidimensional predictive model for 1-year mRS outcomes in acute ischemic stroke.European journal of medical research · 2026Article
- Observational
- Article
- L-shaped association between the ratio of serum albumin to globulin and the risk of all-cause mortality among adults with kidney stones: a national cohort study.Translational andrology and urology · 2025Article
- Albumin-Globulin Ratio and Common Carotid Artery Intima-Media Thickness in Patients with Ischemic Stroke.Current neurovascular research · 2025Article
- Ginseng polysaccharides ameliorate DSS-induced inflammatory bowel disease by regulating gut microbiota in dogs.Frontiers in veterinary science · 2025Article
- Development and validation of a predictive nomogram for cerebral white matter hyperintensities: insights from a comprehensive clinical and laboratory analysis.Frontiers in neuroscience · 2025Article
- Association between serum A/G ratio and stroke: data from NHANES 2009-2020.Frontiers in nutrition · 2025Article
- Association between serum albumin-to-globulin ratio and subtypes of cerebral atherosclerotic stenosis in acute ischemic stroke.Frontiers in neurology · 2025Article
- Comprehensive predictive model for cerebral microbleeds: integrating clinical and biochemical markers.Frontiers in neuroscience · 2024Article
- Assessment of hepatoprotective, nephroprotective efficacy, and antioxidative potential ofFood science & nutrition · 2023Article
- Association of serum albumin to globulin ratio with outcomes in acute ischemic stroke.CNS neuroscience & therapeutics · 2023Article
- Clinical significance of albumin to globulin ratio among patients with stroke-associated pneumonia.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Purpose: Albumin to globulin ratio (A/G) has been established as a representative biomarker for assessing inflammation and nutritional status. However, the prognostic value of A/G has rarely been reported in acute ischemic stroke (AIS) patients with intravenous thrombolysis (IVT). Methods: A total of 311 AIS patients who had undergone IVT and completed 3-month follow-up were retrospectively recruited in this study. Albumin (Alb), globulin (Glb) and A/G on admission, within 24 hours after IVT and on day 7 were recorded. Poor outcome was defined as death or major disability (modified Rankin Scale, 3-6) at 3 months. Results: Among the 311 cases, 260 patients had admission blood samples, 296 cases had blood samples within 24 hours after IVT and 126 cases had blood samples on day 7. The patients with and without available blood samples were well-balanced. During the first 24 h, we observed A/G to increase significantly compared with baseline whereas at day 7 it was almost back to baseline in patients with a poor outcome. Receiver operating characteristic (ROC) curves analysis showed that A/G had a better performance in discriminating patients at high risk and low risk of a poor outcome than either Alb or Glb alone and carried the highest predictive ability on day 7 (AUC = 0.807). Lower 7-day A/G was independently associated with a poor outcome (per-SD increase, OR = 0.182, 95% CI: 0.074-0.446). Conclusion: A/G is an important prognostic indicator for AIS outcomes and merits dynamic monitoring.
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