Evidence map›Paper›PMID 35505689›Full record

ArticleBrain communications2022

Symptoms reported by Canadians posted in Havana are linked with reduced white matter fibre density.

Guillermo Aristi, Lyna Kamintsky, Margaux Ross, Chris Bowen, Cynthia Calkin, Alon Friedman, Javeria A Hashmi

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07267819 (The Efficacy of Xeomin as a Prophylactic Therapy for Migraine in Patients With Traumatic Brain Injuries), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07267819 recruitingnot on this mapstarted 2025, after this paper: background citation

The Efficacy of Xeomin as a Prophylactic Therapy for Migraine in Patients With Traumatic Brain Injuries (TBIs) Versus Anomalous Health Incidents (AHIs)

TypeobservationalSponsorUniformed Services University of the Health SciencesRan2025 to 2028Enrolled60ConditionsMigraine, Traumatic Brain Injury, Anomalous Health IncidentsArmsXeomin (incobotulinumtoxinA)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Guillermo AristiDepartment of Anesthesia, Pain Management & Perioperative Medicine, Dalhousie University, Nova Scotia Health Authority, Halifax, Canada B3H 1V7.
Lyna KamintskyDepartments of Medical Neuroscience, Pediatric and Surgery, Dalhousie University, Nova Scotia Health Authority, Halifax, Canada B3H 4R2.
Margaux RossDepartment of Psychiatry, Dalhousie University, NSHA, Halifax, Canada B3H 1V7.
Chris BowenDepartment of Diagnostic Radiology, Dalhousie University, NSHA, Halifax Canada, B3H 1V7.
Cynthia CalkinDepartment of Psychiatry, Dalhousie University, NSHA, Halifax, Canada B3H 1V7.
Alon FriedmanDepartments of Medical Neuroscience, Pediatric and Surgery, Dalhousie University, Nova Scotia Health Authority, Halifax, Canada B3H 4R2.ORCID https://orcid.org/0000-0003-4780-8456
Javeria A HashmiDepartment of Anesthesia, Pain Management & Perioperative Medicine, Dalhousie University, Nova Scotia Health Authority, Halifax, Canada B3H 1V7.ORCID https://orcid.org/0000-0003-4569-3587
Dalhousie University · CABen-Gurion University of the Negev · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diplomats representing the USA have reported with unusual neurologic symptoms and MRI changes after being posted in Havana, Cuba between late 2016 and 2018. Here, we examined white matter microstructure and network connectivity of individuals stationed in Havana, using diffusion-weighted MRI, fixel-based analysis and structural connectomics as implemented in MRtrix3. MRI data acquisition and clinical assessments were done in a total of 24 diplomats and their family members and 40 healthy controls. The diplomat data were grouped into an exposed cohort (

Indexed as

brain injurydiffusion-weighted MRIHavana syndromeheadachewhite matter

Identifiers

PMID35505689
PMCPMC9050567
OpenAlexW4214809227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.