Evidence map›Paper›PMID 35505681›Full record

Trial reportPeerJ2022

Transcranial direct current stimulation combined with trunk-targeted, proprioceptive neuromuscular facilitation in subacute stroke: a randomized controlled trial.

Jaya Shanker Tedla, Erika Rodrigues, Arthur S Ferreira, Jose Vicente, Ravi Shankar Reddy, Kumar Gular, Devika Rani Sangadala, Venkata Nagaraj Kakaraparthi, Faisal Asiri, Ajaya Kumar Midde and 1 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06999876 (The Effect of Combined Transcranial Pulse Current Stimulation), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06999876 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effect of Combined Transcranial Pulse Current Stimulation (tPCS) and Transcutaneous Electrical Nerve Stimulation (TENS) on Lower Limb Motor Function in Subacute to Chronic Stroke Patients With Hemiplegia: A Double-blind, Sham-controlled, Randomized Controlled Study

TypeinterventionalSponsorNational University Health System, SingaporeRan2025 to 2026Enrolled90ConditionsStroke Patients With Hemiplegia or Hemiparesis in the Subacute StageArmsThe AscenZ-VIII Stimulator (Investigational Medical Device)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Jaya Shanker TedlaDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Aseer, Saudi Arabia.ORCID 0000-0002-2876-4227
Erika RodriguesPostgraduate Program in Rehabilitation Science, University Center Augusto Motta UNISUAM, Rio de Janeiro, Brazil.
Arthur S FerreiraPostgraduate Program in Rehabilitation Science, University Center Augusto Motta UNISUAM, Rio de Janeiro, Brazil.ORCID 0000-0001-7014-2002
Jose VicenteProfessor of Neurological Physiotherapy, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Ravi Shankar ReddyDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Aseer, Saudi Arabia.ORCID 0000-0001-6638-0585
Kumar GularDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Aseer, Saudi Arabia.
Devika Rani SangadalaDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Aseer, Saudi Arabia.
Venkata Nagaraj KakaraparthiDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Aseer, Saudi Arabia.
Faisal AsiriDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Aseer, Saudi Arabia.
Ajaya Kumar MiddeHead of Neurorehabilitation, Department of Physiotherapy, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India.
Snehil DixitDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Aseer, Saudi Arabia.
King Khalid University · SAUniversity Center Augusto Motta · BRKrishna Institute of Medical Sciences · INUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Stroke is the foremost cause of death and disability worldwide. Improving upper extremity function and quality of life are two paramount therapeutic targets during rehabilitation. Aim of the study: To investigate the effects of transcranial direct current stimulation (tDCS) combined with trunk-targeted proprioceptive neuromuscular facilitation (PNF) on impairments, activity limitations, and participation restrictions of subjects with subacute stroke. Methodology: Fifty-four subjects with subacute stroke were divided into three groups using block randomization. All three groups received rehabilitation sessions lasting 90 min in duration, four times per week, for 6 weeks. Group 1 ( Results: A two-way linear mixed model analysis revealed interaction effects (group × time) for all outcome measurements (Trunk Impairment Scale, Fugl-Meyer Assessment of Motor Recovery after stroke upper extremity subsection, Wolf Motor Function Test, 10-Meter Walk Test, and the Stroke-Specific Quality of Life scale; all Conclusion: Trunk-targeted PNF combined with bihemispheric tDCS along with CPT engender larger improvements in upper extremity and trunk impairment, upper limb function, gait speed, and quality of life in the subacute stroke population.

Indexed as

Muscle Stretching ExercisesStrokeStroke RehabilitationTranscranial Direct Current StimulationHumansQuality of LifeRecovery of FunctionPhysical therapyProprioceptive neuromuscular facilitationStrokeTranscranial direct current stimulation

Identifiers

PMID35505681
PMCPMC9057289
OpenAlexW4225002686

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.