Evidence map›Paper›PMID 35505092›Full record

ArticleScientific reports2022

Microencapsulated probiotic Lactiplantibacillus plantarum and/or Pediococcus acidilactici strains ameliorate diarrhoea in piglets challenged with enterotoxigenic Escherichia coli.

Pawiya Pupa, Prasert Apiwatsiri, Wandee Sirichokchatchawan, Nopadon Pirarat, Teerawut Nedumpun, David J Hampson, Nongnuj Muangsin, Nuvee Prapasarakul

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. ProbioticCells · 2026
    Article
  2. ProbioticVeterinary sciences · 2026
    Article
  3. ProbioticJournal of animal science and technology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. ProbioticFrontiers in immunology · 2025
    Article
  10. Review
  11. Translational animal science · 2024
    Article
  12. Effects of dietary supplementation ofJournal of animal science and technology · 2023
    Article
  13. Liquid fermented cereals with addedFrontiers in veterinary science · 2023
    Article
  14. Microorganisms · 2022
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pawiya PupaDepartment of Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Prasert ApiwatsiriDepartment of Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Wandee SirichokchatchawanCollege of Public Health Sciences, Chulalongkorn University (CPHS), Bangkok, Thailand.
Nopadon PiraratDepartment of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Teerawut NedumpunDepartment of Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
David J HampsonSchool of Veterinary Medicine, Murdoch University, Perth, 6150, Australia.
Nongnuj MuangsinDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Nuvee PrapasarakulDepartment of Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand. Nuvee.p@chula.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactiplantibacillus plantarum (strains 22F and 25F) and Pediococcus acidilactici (strain 72N) have displayed antibacterial activity in vitro, suggesting that they could be used to support intestinal health in pigs. The aim of this study was to determine if microencapsulated probiotics could reduce the severity of infection with enterotoxigenic Escherichia coli (ETEC) in weaned pigs. Sixty healthy neonatal piglets were cross-fostered and separated into five groups. Piglets to be given the microencapsulated probiotics received these orally on days 0, 3, 6, 9, and 12. Only piglets in groups 1 and 5 did not receive probiotics: those in groups 2 and 4 received the three microencapsulated probiotic strains (multi-strain probiotic), and piglets in group 3 received microencapsulated P. acidilactici strain 72N. After weaning, the pigs in groups 3-5 were challenged with 5 mL (at 10

Indexed as

Enterotoxigenic Escherichia coliPediococcus acidilacticiProbioticsSwine DiseasesAnimalsDiarrheaSwine

Identifiers

PMID35505092
PMCPMC9065055

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.