Evidence map›Paper›PMID 35504836›Full record

ArticleEuropean urology focus2022

Diet and Health-related Quality of Life Among Men on Active Surveillance for Early-stage Prostate Cancer: The Men's Eating and Living Study (Cancer and Leukemia Group 70807 [Alliance]).

J Kellogg Parsons, David Zahrieh, Devin Patel, James L Mohler, Ronald C Chen, Electra D Paskett, Heshan Liu, Elizabeth S Peil, Cheryl L Rock, Olwen Hahn and 7 more

Open access · greenAbstract read
In one paragraph

Article in European urology focus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Review
  3. Western Dietary Pattern, Prudent Dietary Pattern, and Cancer-Specific Quality of Life in Prostate Cancer Survivors in the Health Professionals Follow-Up Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 1 country.

J Kellogg ParsonsJanssen Research and Development, LLC, La Jolla, CA, USA; Department of Urology, University of Michigan, Ann Arbor, MI, USA.
David ZahriehAlliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN, USA. Electronic address: zahrieh.david@mayo.edu.
Devin PatelDepartment of Urology, UC San Diego Moores Comprehensive Cancer Center, La Jolla, CA, USA; VA San Diego Healthcare System, La Jolla, CA, USA.
James L MohlerDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Ronald C ChenDepartment of Radiation Oncology, University of Kansas Cancer Center, Kansas City, KS, USA.
Electra D PaskettDepartment of Medicine, College of Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
Heshan LiuAlliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN, USA.
Elizabeth S PeilAlliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN, USA.
Cheryl L RockDepartment of Family Medicine, University of California, San Diego, La Jolla, CA, USA; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Olwen HahnAlliance Central Protocol Operations, University of Chicago, Chicago, IL, USA.
John TaylorAlliance Central Protocol Operations, University of Chicago, Chicago, IL, USA.
Peter J Van VeldhuizenUniversity of Rochester, Rochester, NY, USA.
Eric J SmallUCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.
Michael J MorrisMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Michelle J NaughtonDepartment of Medicine, College of Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
John P PierceMoores Cancer Center, University of California, San Diego, La Jolla, CA, USA; Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA.
James MarshallDepartment of Prevention and Population Sciences, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Mayo Clinic · USRoswell Park Comprehensive Cancer Center · USThe Ohio State University · USIndo-American Center · USMemorial Sloan Kettering Cancer Center · USThe University of Kansas Cancer Center · USUCSF Helen Diller Family Comprehensive Cancer Center · USUniversity of Chicago · USUniversity of Rochester · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
SWOG Network Group Operations Center of the NCTNU10CA180888 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PRIMO N. LARA · 2014 to 2026
$152.1M
Collaborations and NCORP Collective ManagementUG1CA189823 · NCI · MAYO CLINIC ROCHESTER · PI Evanthia Galanis, Olwen Hahn · 2014 to 2026
$120.6M
Network Lead Academic Participating Site: Memorial Sloan Kettering Cancer CenterUG1CA233290 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CAROL AGHAJANIAN, Darren Feldman · 2019 to 2026
$10.2M
OSU as a Network Lead Academic Participating Site for the NCI NCTNUG1CA233331 · NCI · OHIO STATE UNIVERSITY · PI John L. Hays, Dwight H. Owen · 2019 to 2026
$8.9M
Rochester Network Lead Academic Participating SiteUG1CA233230 · NCI · UNIVERSITY OF ROCHESTER · PI Paul M Barr · 2019 to 2026
$6.9M
UG1 - NCTN (Network Lead)UG1CA233327 · NCI · UNIVERSITY OF CHICAGO · PI STEVEN J CHMURA, HEDY L KINDLER · 2019 to 2026
$4.4M
Network Lead Academic Participating Site Grant from the Roswell Park Cancer InstituteUG1CA233191 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI LELE, SHASHIKANT, LEVINE, ELLIS G · 2019 to 2025
$3.1M
Diet change among prostate cancer patients under expectant managementR01CA132951 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARSHALL, JAMES · 2009 to 2015
$2.4M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA132951NCI NIH HHS U10 CA180888NCI NIH HHS UG1 CA189823NCI NIH HHS UG1 CA233191NCI NIH HHS UG1 CA233230NCI NIH HHS UG1 CA233290NCI NIH HHS UG1 CA233327NCI NIH HHS UG1 CA233331
6 · The paper itself

Abstract

backgroundHealth-related quality of life (HRQoL) among patients with localized prostate cancer (PC) on active surveillance (AS) and whether it may be improved through lifestyle-focused interventions remain underdefined.

objectiveTo assess longitudinal changes in HRQoL in patients who received and those who did not receive a behavioral intervention that increased vegetable intake. DESIGN, SETTING, AND

participantsA secondary analysis of participants in the Men's Eating and Living (MEAL) study (Cancer and Leukemia Group 70807 [Alliance]), a randomized trial of vegetable consumption in patients on AS, was conducted. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Patient-reported outcomes (PROs) included the Memorial Anxiety Scale for Prostate Cancer (MAX-PC), the Expanded Prostate Cancer Index Composite 26 (EPIC-26), and the Functional Assessment of Cancer Therapy Scale-Prostate (FACT-P). Areas under the curves (AUCs) were used to summarize serial HRQoL. RESULTS AND LIMITATIONS: PROs were completed in 87% (n = 387) of the intention-to-collect population. Baseline characteristics of patients completing HRQoL measures did not differ significantly from the entire study population or between groups. Baseline scores were high for all PROs and remained stable over 24 mo, with no significant differences from baseline at any time point. In adjusted analyses, there were no significant differences in summary AUC measures comparing control with intervention for the total MAX-PC score (p = 0.173); EPIC-26 domains of urinary incontinence (p = 0.210), urinary obstruction (p = 0.062), bowel health (p = 0.607), sexual health (p = 0.398), and vitality (p = 0.363); and total FACT-P scores (p = 0.471).

conclusionsAmong men with localized PC on AS enrolled in a randomized trial, HRQoL was high across multiple domains at baseline, remained high during follow-up, and did not change in response to a behavioral intervention that increased vegetable intake. PATIENT SUMMARY: Patients with localized prostate cancer enrolled on active surveillance experience minimal cancer-associated anxiety, suffer low levels of cancer-associated symptoms, and perceive high physical and emotional well-being.

Indexed as

LeukemiaProstatic NeoplasmsDietHumansMaleProstateQuality of LifeWatchful WaitingCancer preventionHealth-related quality of lifeProstate cancer

Identifiers

PMID35504836
PMCPMC10365132
OpenAlexW4225121171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.