Evidence map›Paper›PMID 35504769›Full record

Observational studyClinical nutrition (Edinburgh, Scotland)2022

Nutritional intake and gastro-intestinal symptoms in critically ill COVID-19 patients.

P L M Lakenman, J C van Schie, B van der Hoven, S J Baart, R D Eveleens, J van Bommel, J F Olieman, K F M Joosten

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Clinical nutrition (Edinburgh, Scotland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

P L M LakenmanDivision of Dietetics, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands. Electronic address: p.lakenman@erasmusmc.nl.
J C van SchieDivision of Dietetics, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands.
B van der HovenDepartment of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands.
S J BaartDepartment of Biostatistics and Epidemiology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
R D EveleensDepartment of Anaesthesiology, Amsterdam UMC, Amsterdam, the Netherlands.
J van BommelDepartment of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands.
J F OliemanDivision of Dietetics, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands.
K F M JoostenIntensive Care Unit, Department of Paediatrics and Paediatric Surgery, Erasmus Medical Centre - Sophia Children's Hospital, Rotterdam, the Netherlands.
Erasmus MC · NLErasmus University Rotterdam · NLAmsterdam University Medical Centers · NLErasmus MC - Sophia Children’s Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

aimsCritically ill COVID-19 patients seem hypermetabolic and difficult to feed enterally, due to gastro-intestinal (GI) symptoms such as high gastric residual volumes (GRV) and diarrhea. Our aim was to describe the association of nutritional intake and GI symptoms during first 14 days of ICU admission.

methodsObservational study including critically ill adult COVID-19 patients. Data on nutritional intake [enteral nutrition (EN) or parenteral nutrition] and GI symptoms were collected during 14 days after ICU admission. Target energy and protein feeding goals were calculated conform ESPEN guidelines. GI symptoms included GRV (ml/d), vomiting, abdominal distension, and faeces (ml/d). High GRV's were classified as ≥2 times ≥150 ml/d and diarrhea as Bristol stool chart ≥6. GI symptoms were defined as mild if at least one symptom occurred and as moderate when ≥2 symptoms occurred. Acute gastrointestinal injury (AGI) grades of III were classified as GI dysfunction and grades of IV were considered as GI failure with severe impact on distant organs. Linear mixed model analysis was performed to explore the development of nutritional intake and GI symptoms over time at day (D) 0, 4, 10, and 14.

resultsOne hundred and fifty patients were included [75% male; median age 64 years (IQR 54-70)]. BMI upon admission was 28 kg/m

conclusionOccurrence of GI symptoms was limited and seems no major barrier for EN in our group of critically COVID-19 patients. Nutritional intake was just below requirements during the first 14 days of ICU admission. The effect on nutritional status remains to be studied.

Indexed as

COVID-19Gastrointestinal DiseasesAdultCritical IllnessDiarrheaEatingFemaleHumansIntensive Care UnitsMaleMiddle AgedCOVID-19Critically ill patientsEnteral nutritionGastro-intestinal symptoms

Identifiers

PMID35504769
PMCPMC8986274
OpenAlexW4224304924

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.