Evidence map›Paper›PMID 35504727›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

ASD/OCD-Linked Protocadherin-10 Regulates Synapse, But Not Axon, Development in the Amygdala and Contributes to Fear- and Anxiety-Related Behaviors.

Naosuke Hoshina, Erin M Johnson-Venkatesh, Veronica R Rally, Jaanvi Sant, Miyuki Hoshina, Mariel P Seiglie, Hisashi Umemori

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  5. Proteomic Signatures of ProtectedmedRxiv : the preprint server for health sciences · 2026
    Article
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  7. Long-read whole-genome sequencing of SHR rat substrains with distinct substance use phenotypes.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
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  16. The role of Pcdh10 in neurological disease and cancer.Journal of cancer research and clinical oncology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Naosuke HoshinaDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Erin M Johnson-VenkateshDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.ORCID https://orcid.org/0000-0003-2590-0737
Veronica R RallyDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Jaanvi SantDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Miyuki HoshinaDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Mariel P SeiglieDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Hisashi UmemoriDepartment of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115 hisashi.umemori@childrens.harvard.edu.ORCID https://orcid.org/0000-0001-7198-2062
Boston Children's Hospital · US

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
Molecular Codes for the Establishment of Functionally Segregated Dopaminergic CircuitsR01MH125162 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI UMEMORI, HISASHI, WATABE-UCHIDA, MITSUKO · 2021 to 2025
$4.1M
Finding the projection-specific dopaminergic synaptic organizersR01DA042744 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori, Mitsuko Watabe-Uchida · 2017 to 2026
$3.9M
NICHD NIH HHS P50 HD105351NIDA NIH HHS R01 DA042744NIMH NIH HHS R01 MH125162
6 · The paper itself

Abstract

The

Indexed as

Autism Spectrum DisorderObsessive-Compulsive DisorderAmygdalaAnimalsAnxietyFearHumansMaleMiceProtocadherinsSynapsesProtocadherinsautism spectrum disorderbasolateral nucleus of the amygdalafear and anxietyobsessive-compulsive disorderPCDH10synapse development

Identifiers

PMID35504727
PMCPMC9145243
OpenAlexW4225381882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.