ArticleNeuroImage2022
Dynamic trajectories of connectome state transitions are heritable.
Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Forecasting Perception Before It Happens: Context-Specific Connectivity Patterns Predict Perceptual Outcomes.bioRxiv : the preprint server for biology · 2026Article
- Time Persistence of the FMRI Resting-State Functional Brain Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Modulatory Neurotransmitter Genotypes Shape Dynamic Functional Connectome Reconfigurations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Tai Chi Practice Buffers Aging Effects in Functional Brain Connectivity.Brain sciences · 2024Article
- Rapid dynamics of electrophysiological connectome states are heritable.bioRxiv : the preprint server for biology · 2024Article
- Cognitive abilities are associated with rapid dynamics of electrophysiological connectome states.bioRxiv : the preprint server for biology · 2024Article
- Rapid dynamics of electrophysiological connectome states are heritable.Network neuroscience (Cambridge, Mass.) · 2024Article
- Cognitive abilities are associated with rapid dynamics of electrophysiological connectome states.Network neuroscience (Cambridge, Mass.) · 2024Article
- Neurogenetics of Brain Connectivity: Current Approaches to the Study (Review).Sovremennye tekhnologii v meditsine · 2024Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The brain's functional connectome is dynamic, constantly reconfiguring in an individual-specific manner. However, which characteristics of such reconfigurations are subject to genetic effects, and to what extent, is largely unknown. Here, we identified heritable dynamic features, quantified their heritability, and determined their association with cognitive phenotypes. In resting-state fMRI, we obtained multivariate features, each describing a temporal or spatial characteristic of connectome dynamics jointly over a set of connectome states. We found strong evidence for heritability of temporal features, particularly, Fractional Occupancy (FO) and Transition Probability (TP), representing the duration spent in each connectivity configuration and the frequency of shifting between configurations, respectively. These effects were robust against methodological choices of number of states and global signal regression. Genetic effects explained a substantial proportion of phenotypic variance of these features (h
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.