Evidence map›Paper›PMID 35504021›Full record

ArticleScience (New York, N.Y.)2022

Response to Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis".

J Terreros-Roncal, E P Moreno-Jiménez, M Flor-García, C B Rodríguez-Moreno, M F Trinchero, B Márquez-Valadez, F Cafini, A Rábano, M Llorens-Martín

Open access · greenAbstract readComment
In one paragraph

Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Isolation of Adult Hippocampal Neural Stem Cells.Methods in molecular biology (Clifton, N.J.) · 2025
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  2. Article
  3. Review
  4. Review
  5. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

J Terreros-Roncal *Department of Molecular Neuropathology, Centro de Biología Molecular "Severo Ochoa," Spanish Research Council (CSIC)-Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0003-4247-6368
E P Moreno-Jiménez *Department of Molecular Neuropathology, Centro de Biología Molecular "Severo Ochoa," Spanish Research Council (CSIC)-Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0002-9865-4875
M Flor-García *Department of Molecular Neuropathology, Centro de Biología Molecular "Severo Ochoa," Spanish Research Council (CSIC)-Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0002-6938-9689
C B Rodríguez-MorenoDepartment of Molecular Neuropathology, Centro de Biología Molecular "Severo Ochoa," Spanish Research Council (CSIC)-Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0003-0738-7597
M F TrincheroLaboratory of Neuronal Plasticity, Leloir Institute (IIBBA-CONICET), Buenos Aires, Argentina.ORCID 0000-0001-7633-2106
B Márquez-ValadezDepartment of Molecular Neuropathology, Centro de Biología Molecular "Severo Ochoa," Spanish Research Council (CSIC)-Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0001-7812-2284
F CafiniFaculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain.
A RábanoNeuropathology Department, CIEN Foundation, Madrid, Spain.ORCID 0000-0001-9320-6566
M Llorens-MartínDepartment of Molecular Neuropathology, Centro de Biología Molecular "Severo Ochoa," Spanish Research Council (CSIC)-Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0001-9129-5198
Biomedical Research Networking Center on Neurodegenerative Diseases · ESConsejo Nacional de Investigaciones Científicas y Técnicas · ARFundacion Centro De Investigacion De Enfermedades Neurologicas · ESUniversidad Europea de Madrid · ES

Funding

European Research Council 101001916
6 · The paper itself

Abstract

Rakic and colleagues challenge the use of extensively validated adult hippocampal neurogenesis (AHN) markers and postulate an alternative interpretation of some of the data included in our study. In Terreros-Roncal

Indexed as

HippocampusNeurodegenerative DiseasesNeurogenesisAdultBiomarkersHumansBiomarkers

Identifiers

PMID35504021
PMCPMC7613470
OpenAlexW4223922082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.