ArticlePloS one2022
Effect of ultraviolet C emitted from KrCl excimer lamp with or without bandpass filter to mouse epidermis.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Reactive oxygen species generated by irradiation with bandpass-filtered 222-nm Far-UVC play an important role in the germicidal mechanism toApplied and environmental microbiology · 2025Article
- The new 222-nm far ultraviolet-C lowers bacterial contamination to endoscopists during esophagogastroduodenoscopy.DEN open · 2024Article
- Wavelength dependence of ultraviolet light inactivation for SARS-CoV-2 omicron variants.Scientific reports · 2023Article
- Solid-State Far-Ultraviolet C Light Sources for the Disinfection of Pathogenic Microorganisms Using Graphene Nanostructure Field Emitters.Global challenges (Hoboken, NJ) · 2023Article
- Far-UVC Radiation for Disinfecting Hands or Gloves?Pathogens (Basel, Switzerland) · 2023Article
- Active Air Interventions.The Bridge · 2022Article
- Virus inactivation and skin safety studies using far-UVC LEDs.Photochemistry and photobiologyArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been reported that 222-nm ultraviolet C (UVC) exerts a germicidal effect on bacteria and viruses as well as UV radiation emitted from a conventional germicidal lamp but is less toxic to the mammalian cells than that from a germicidal lamp. An excimer lamp filled with krypton chloride (KrCl) gas principally emits 222-nm UVC. However, the lamp also emits a wide band of wavelengths other than 222 nm, especially UVC at a longer wavelength than 222 nm and ultraviolet B, which cause DNA damage. There are some reports on the critical role of bandpass filters in reducing the harmful effect of UVC emitted from a KrCl excimer lamp in a human skin model and human subjects. However, the effectiveness of a bandpass filter has not been demonstrated in animal experiments. In the present study, mice were irradiated with UVC emitted from a KrCl excimer lamp with or without a bandpass filter. UVC emitted from an unfiltered KrCl lamp at doses of 50, 150 and 300 mJ/cm2 induced cyclobutyl pyrimidine dimer (CPD)-positive cells, whereas UVC emitted from a filtered lamp did not significantly increase CPD-positive cells in the epidermis. The present study suggested that the bandpass filter serves a critical role in reducing the harmful effect of emission outside of 222 nm to mouse keratinocytes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.