ArticlePlant cell reports2022
Synergetic modulation of plant cadmium tolerance via MYB75-mediated ROS homeostasis and transcriptional regulation.
Article in Plant cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Transporter promiscuity and redox-driven metal partitioning in plant responses to chemically analogous metals.Plant cell reports · 2026Review
- ChERF017, an ERF transcription factor, confers cadmium stress tolerance in Cerasus humilis.BMC plant biology · 2026Article
- Evaluation of the genes CYPEnvironmental science and pollution research international · 2026Article
- A NAC transcription factor MdNAC1 enhances cadmium tolerance in apple.Plant cell reports · 2026Article
- Cadmium Stress Disrupts Auxin Signaling and Growth inPlants (Basel, Switzerland) · 2026Article
- Selenium Alleviates Cadmium Toxicity by Regulating Carbon Metabolism, AsA-GSH Cycle, and Cadmium Transport inPlants (Basel, Switzerland) · 2025Article
- Microrchidia OsMORC6 Positively Regulates Cadmium Tolerance and Uptake by Mediating DNA Methylation in Rice.Rice (New York, N.Y.) · 2025Article
- GHCYP706A7 governs anthocyanin biosynthesis to mitigate ROS under alkali stress in cotton.Plant cell reports · 2025Article
- β-cyclocitral as a cross-species mediator of abiotic stress signaling: insights and future directions toward crop improvement.Frontiers in plant science · 2025Review
- An Overview of the Mechanisms through Which Plants Regulate ROS Homeostasis under Cadmium Stress.Antioxidants (Basel, Switzerland) · 2024Review
- Metal transport proteins and transcription factor networks in plant responses to cadmium stress.Plant cell reports · 2024Review
- The Uptake, Transfer, and Detoxification of Cadmium in Plants and Its Exogenous Effects.Cells · 2024Review
- Transcription factors involved in plant responses to cadmium-induced oxidative stress.Frontiers in plant science · 2024Review
- Genome-Wide Identification of PAP1 Direct Targets in Regulating Seed Anthocyanin Biosynthesis inInternational journal of molecular sciences · 2023Article
- Reactive Oxygen Species: A Crosslink between Plant and Human Eukaryotic Cell Systems.International journal of molecular sciences · 2023Review
- The Effect of Cadmium on Plants in Terms of the Response of Gene Expression Level and Activity.Plants (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
key messageMYB75 enhances plant cadmium tolerance by mediating ROS homeostasis and cadmium tolerance-related genes expression. Cadmium (Cd) is a heavy metal with biological toxicity, which can be detoxified through chelation and compartmentation in plants. Transcriptional regulation mediates plant Cd tolerance by modulating these processes. However, the mechanism remains to be studied. Our results showed a previously unknown function of MYB75 transcription factor in the regulation of Cd tolerance. Cd exposure stimulates anthocyanin accumulation by raising MYB75 expression. Enhanced Cd tolerance was observed in the MYB75-overexpressing plants, whereas increased Cd sensitivity was found in the MYB75 loss-of-function mutants. Under Cd stress conditions, lower reactive oxygen species (ROS) levels were detected in MYB75-overexpressing plants than in wild type plants. In contrast, higher ROS levels were found in MYB75 loss-of-function mutants. Overexpression of MYB75 was associated with increased glutathione (GSH) and phytochelatin (PC) content under Cd exposure. Furthermore, the expression of Cd stress-related gene including ACBP2 and ABCC2 was elevated in MYB75-overexpressing plants, and this upregulation was mediated through the mechanism by which MYB75 directly bind to the promoter of ACBP2 and ABCC2. Our findings reveal an important role for MYB75 in the regulation of plant Cd tolerance via anthocyanin-mediated ROS homeostasis, and through upregulation of Cd stress-related gene at the transcriptional level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.