ArticleJournal of nephrology2022
Specificity of severe AKI aetiology and care in the elderly. The IRACIBLE prospective cohort study.
Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03192189 (Development of a Decision-making Aid for Referring Severe Kidney Injury Patients for Nephrology Consultations), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Development of a Decision-making Aid for Referring Severe Kidney Injury Patients for Nephrology Consultations
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0 citing papers in PubMed, 2 citations in OpenAlex.
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
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Abstract
introductionAcute Kidney Injury (AKI) is increasingly common in people over 65 years of age, but its causes and management are poorly described. The purpose of this study was to describe the causes, management and prognosis of patients over 65 hospitalised for severe acute kidney injury (AKI) in all departments of a tertiary centre.
methodThe prospective IRACIBLE (IRA: AKI in French; CIBLE: target in French) cohort included 480 patients hospitalised at a university hospital over 18 months for severe AKI or subgroup of AKIN3 (Acute Kidney Injury Network classification) defined by an acute creatinine increase > 354 μmol/L or managed with acute renal replacement therapy (RRT). The history, aetiology of AKI, management, and prognosis were compared in three age groups: < 65, 65-75, and > 75 years.
resultsThe study population included 480 subjects (73% men) with a median body mass index (BMI) of 26.6 kg/m
conclusionOlder patients hospitalised for severe AKI have a specific profile with more comorbidities, lower baseline renal function, an aetiology of AKI of mainly extra-parenchymal causes and a complex pathway of care with an overall poor prognosis.
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