Evidence map›Paper›PMID 35503014›Full record

ArticleRadiology2022

Resting-State Functional MRI of Healthy Adults: Temporal Dynamic Brain Coactivation Patterns.

Tiantian Liu, Li Wang, Dingjie Suo, Jian Zhang, Kexin Wang, Jue Wang, Duanduan Chen, Tianyi Yan

Abstract read
PubMed Publisher
In one paragraph

Article in Radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  9. Brain network dynamics in patients with single- and multiple-domain amnestic mild cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Tiantian LiuFrom the School of Life Science (T.L., L.W., D.S., K.W., J.W., D.C., T.Y.) and Intelligent Robotics Institute, School of Mechatronical Engineering (J.Z.), Beijing Institute of Technology, 5 South Zhongguancun St, Haidian District, Beijing 100081, China.ORCID 0000-0001-7816-9824
Li WangFrom the School of Life Science (T.L., L.W., D.S., K.W., J.W., D.C., T.Y.) and Intelligent Robotics Institute, School of Mechatronical Engineering (J.Z.), Beijing Institute of Technology, 5 South Zhongguancun St, Haidian District, Beijing 100081, China.
Dingjie SuoFrom the School of Life Science (T.L., L.W., D.S., K.W., J.W., D.C., T.Y.) and Intelligent Robotics Institute, School of Mechatronical Engineering (J.Z.), Beijing Institute of Technology, 5 South Zhongguancun St, Haidian District, Beijing 100081, China.ORCID 0000-0002-2797-1240
Jian ZhangFrom the School of Life Science (T.L., L.W., D.S., K.W., J.W., D.C., T.Y.) and Intelligent Robotics Institute, School of Mechatronical Engineering (J.Z.), Beijing Institute of Technology, 5 South Zhongguancun St, Haidian District, Beijing 100081, China.ORCID 0000-0003-1327-7896
Kexin WangFrom the School of Life Science (T.L., L.W., D.S., K.W., J.W., D.C., T.Y.) and Intelligent Robotics Institute, School of Mechatronical Engineering (J.Z.), Beijing Institute of Technology, 5 South Zhongguancun St, Haidian District, Beijing 100081, China.ORCID 0000-0002-4445-806X
Jue WangFrom the School of Life Science (T.L., L.W., D.S., K.W., J.W., D.C., T.Y.) and Intelligent Robotics Institute, School of Mechatronical Engineering (J.Z.), Beijing Institute of Technology, 5 South Zhongguancun St, Haidian District, Beijing 100081, China.
Duanduan ChenFrom the School of Life Science (T.L., L.W., D.S., K.W., J.W., D.C., T.Y.) and Intelligent Robotics Institute, School of Mechatronical Engineering (J.Z.), Beijing Institute of Technology, 5 South Zhongguancun St, Haidian District, Beijing 100081, China.
Tianyi YanFrom the School of Life Science (T.L., L.W., D.S., K.W., J.W., D.C., T.Y.) and Intelligent Robotics Institute, School of Mechatronical Engineering (J.Z.), Beijing Institute of Technology, 5 South Zhongguancun St, Haidian District, Beijing 100081, China.ORCID 0000-0002-2674-4134

Funding

Biotechnology and Biological Sciences Research Council BB/H008217/1Medical Research Council
6 · The paper itself

Abstract

Background The aging brain is typically associated with aberrant interactions of large-scale intrinsic networks. However, the dynamic variation of these networks' coactivation or deactivation across the adult lifespan remains unclear. Purpose To promote the interpretation of dynamic brain network variations underlying the complex aging process by quantifying activation levels and obtaining a clear definition of coactivation patterns (CAPs) with resting-state functional MRI (rsfMRI). Materials and Methods In a retrospective study (October 2010 to September 2013), rsfMRI data from healthy participants in the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) data repository were used to generate CAPs by applying single-volume temporal clustering analysis. Spatial clustering analysis was then performed to capture dynamic coactivation and deactivation within or between primary sensory networks and high-order cognitive networks (including the default mode network [DMN], attentional network [AN], and frontoparietal network [FPN]). Linear relationships between dynamic metrics and age were revealed with Spearman partial correlations. Results A total of 614 participants (mean age, 54 years ± 18 [SD]; 311 women) ranging in age from 18 to 88 years were evaluated. There was a negative correlation of the CAPs (Spearman correlations:

Indexed as

BrainMagnetic Resonance ImagingAdolescentAdultAgedAged, 80 and overAgingBrain MappingFemaleHumansMiddle AgedNeural PathwaysRetrospective StudiesYoung Adult

Identifiers

PMID35503014

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.