Evidence map›Paper›PMID 35502784›Full record

ArticleDevelopment (Cambridge, England)2022

Non-traditional roles of immune cells in regeneration: an evolutionary perspective.

Beryl N Arinda, Yacoub A Innabi, Juris A Grasis, Néstor J Oviedo

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Immune cells in cardiac repair and regeneration.Development (Cambridge, England) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Beryl N ArindaDepartment of Molecular and Cell Biology, University of California, Merced, CA 95343, USA.ORCID 0000-0001-9249-0120
Yacoub A InnabiDepartment of Molecular and Cell Biology, University of California, Merced, CA 95343, USA.ORCID 0000-0002-5294-1254
Juris A GrasisDepartment of Molecular and Cell Biology, University of California, Merced, CA 95343, USA.ORCID 0000-0002-3945-0135
Néstor J OviedoDepartment of Molecular and Cell Biology, University of California, Merced, CA 95343, USA.ORCID 0000-0002-0213-9781
University of California, Merced · US

Funding

The Effects of Direct Current Stimulation in Adult TissuesR01GM132753 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI OVIEDO, NESTOR J · 2019 to 2022
$1.2M
NIGMS NIH HHS R01 GM132753NIGMS NIH HHS R01GM132753
6 · The paper itself

Abstract

Immune cells are known to engage in pathogen defense. However, emerging research has revealed additional roles for immune cells, which are independent of their function in the immune response. Here, we underscore the ability of cells outside of the adaptive immune system to respond to recurring infections through the lens of evolution and cellular memory. With this in mind, we then discuss the bidirectional crosstalk between the immune cells and stem cells and present examples where these interactions regulate tissue repair and regeneration. We conclude by suggesting that comprehensive analyses of the immune system may enable biomedical applications in stem cell biology and regenerative medicine.

Indexed as

Immunity, InnateRegenerative MedicineImmune SystemStem CellsWound HealingHemocytesHomeostasisInnate immunityMacrophagesRegenerationStem cellsTrained immunity

Identifiers

PMID35502784
PMCPMC9124569
OpenAlexW4225405006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.