ArticleJournal of the Royal Society of Medicine2022
The role of systematic reviews in identifying the limitations of preclinical animal research, 2000-2022: part 1.
Article in Journal of the Royal Society of Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Probiotics and Their Functional Role in Mitigating Antinutrient Effects In Vivo-A Systematic Review and Meta-Analysis.Comprehensive reviews in food science and food safety · 2026Pooled it
- Therapeutic effects and mechanisms of Tripterygium wilfordii extracts in rheumatoid arthritis: a systematic review and meta-analysis of preclinical studies.Scientific reports · 2025Pooled it
- Oleanolic acid and its derivatives in breast cancer therapy: mechanistic insights, structural modifications, and novel delivery strategies.Frontiers in pharmacology · 2026Review
- How long does it take to complete and publish a systematic review of animal studies?BMC medical research methodology · 2025Article
- Quality, topics, and demographic trends of animal systematic reviews - an umbrella review.Journal of translational medicine · 2025Review
- Toward a roadmap for addressing today's health dilemma-The 101-statement consensus report.Frontiers in nutrition · 2025Article
- Use and reporting of systematic review methodology in EFSA scientific opinions on animal health and welfare.Frontiers in veterinary science · 2025Article
- A sociological perspective on the challenges of displacing animal research within academia: the contribution of Bourdieu.NAM journal · 2025Article
- STEED: A data mining tool for automated extraction of experimental parameters and risk of bias items from in vivo publications.PloS one · 2024Article
- From data deluge to publomics: How AI can transform animal research.Lab animal · 2023Article
- The role of systematic reviews in identifying the limitations of preclinical animal research, 2000-2022: part 2.Journal of the Royal Society of Medicine · 2022Article
- Mitigating animal methods bias to reduce animal use and improve biomedical translation.Science progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.