Evidence map›Paper›PMID 35502553›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2022

Lessons Learned from the Impact of COVID-19 on NCI-sponsored Cancer Prevention Clinical Trials: Moving Toward Participant-centric Study Designs.

Goli Samimi, Margaret House, Kelly Benante, Lisa Bengtson, Troy Budd, Bridget Dermody, Katina DeShong, Valerie Dyer, Bruce F Kimler, Vikrant V Sahasrabuddhe and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Goli Samimi *Division of Cancer Prevention, NCI, Rockville, Maryland.
Margaret House *Division of Cancer Prevention, NCI, Rockville, Maryland.ORCID 0000-0001-6887-1046
Kelly BenanteRobert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois.ORCID 0000-0002-4014-6560
Lisa BengtsonDivision of Cancer Prevention, NCI, Rockville, Maryland.ORCID 0000-0002-2788-6548
Troy BuddDivision of Cancer Prevention, NCI, Rockville, Maryland.
Bridget DermodyUniversity of Wisconsin-Madison, Madison, Wisconsin.
Katina DeShongUniversity of Wisconsin-Madison, Madison, Wisconsin.
Valerie DyerDivision of Cancer Prevention, NCI, Rockville, Maryland.
Bruce F KimlerUniversity of Kansas Medical Center, Kansas City, Kansas.ORCID 0000-0001-7021-6964
Vikrant V SahasrabuddheDivision of Cancer Prevention, NCI, Rockville, Maryland.
Suzanne SiminskiFrontier Science Foundation, Amherst, New York.
Leslie G FordDivision of Cancer Prevention, NCI, Rockville, Maryland.ORCID 0000-0003-2412-8028
Eduardo Vilar *Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0001-6404-3761
Eva Szabo *Division of Cancer Prevention, NCI, Rockville, Maryland.ORCID 0000-0003-3891-0942
Center for Cancer Research · USUniversity of Wisconsin–Madison · USFrontier Science & Technology Research Foundation · USNorthwestern University · USThe University of Texas MD Anderson Cancer Center · USUniversity of Kansas Medical Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
CP-CTNet Coordinating Center Year 6 - Aug 1, 2024 through July 31, 2025U24CA242637 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI EICKHOFF, JENS · 2019 to 2024
$14.2M
Northwestern Cancer Prevention ConsortiumUG1CA242643 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SEEMA Ahsan KHAN · 2019 to 2026
$11.9M
University of Arizona Cancer Prevention Clinical Trials Network (UA CP-CTNet)UG1CA242596 · NCI · UNIVERSITY OF ARIZONA · PI Julie E Bauman, Patricia Ann Thompson · 2019 to 2026
$11.5M
iCAN PREVENT: MD Anderson International Cancer Prevention Clinical Trials ConsortiumUG1CA242609 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Eduardo Vilar Sanchez · 2019 to 2026
$10.5M
Early Phase Clinical Cancer Prevention ConsortiumUG1CA242632 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Zora Djuric, Scott Michael Schuetze · 2020 to 2026
$10.0M
The MW Cancer Prevention Clinical Trials NetworkUG1CA242635 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BARROILHET, LISA M · 2020 to 2024
$7.4M
NCI NIH HHS P30 CA016672NCI NIH HHS U24 CA242637NCI NIH HHS UG1 CA242596NCI NIH HHS UG1 CA242609NCI NIH HHS UG1 CA242632NCI NIH HHS UG1 CA242635NCI NIH HHS UG1 CA242643
6 · The paper itself

Abstract

The COVID-19 pandemic overloaded health care systems around the globe and brought travel restrictions and other mandates. These effects critically impacted cancer care and conduct of clinical trials, and required medical and research communities to incorporate changes and novel flexible workflows within clinical trials and regulations to improve efficiency. We report the impact of the pandemic on cancer prevention clinical trials managed by the Division of Cancer Prevention within the NCI, focusing on participant-centric, study staff-centric and regulatory elements. Learning lessons from this challenging period, the cancer prevention community has the opportunity to incorporate many of these necessitated novel approaches to future design of clinical trials, to streamline and improve clinical trial efficiency and impact.

Indexed as

Clinical Trials as TopicCOVID-19NeoplasmsDelivery of Health CareHumansNational Cancer Institute (U.S.)PandemicsResearch DesignUnited States

Identifiers

PMID35502553
PMCPMC11756932
OpenAlexW4225389481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.