Evidence map›Paper›PMID 35502514›Full record

ArticlePediatric pulmonology2022

Obesity is a risk factor for decrease in lung function after COVID-19 infection in children with asthma.

Elif Soyak Aytekin, Umit M Sahiner, Sevda Tuten Dal, Hilal Unsal, Ozan Hakverdi, Berna Oguz, Yasemin Ozsurekci, Bulent E Sekerel, Ozge Soyer

Open access · greenAbstract readComparative Study
In one paragraph

Article in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Observational
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Elif Soyak AytekinDepartment of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey.ORCID 0000-0002-2329-7543
Umit M SahinerDepartment of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey.
Sevda Tuten DalDepartment of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey.
Hilal UnsalDepartment of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey.
Ozan HakverdiDepartment of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey.
Berna OguzDepartment of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.
Yasemin OzsurekciDepartment of Pediatric Infectious Disease, Hacettepe University School of Medicine, Ankara, Turkey.
Bulent E SekerelDepartment of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey.
Ozge SoyerDepartment of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey.ORCID 0000-0002-7444-251X
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIt is not clear whether asthma, the most frequent chronic disease in childhood, is a risk for severe SARS-CoV-2 infection in the pediatric population and how SARS-CoV-2 infection affects the lung functions in these patients. PURPOSE: We aimed to investigate the course and the consequences of SARS-CoV-2 infection among children with asthma and determine the risk factors for the decline in lung function tests (LFTs).

methodsIn this retrospective study, asthmatic children with coronavirus disease 2019 (COVID-19) were compared with a random control group of asthmatic patients without COVID-19. In addition, the clinical course and the effect on LFTs of COVID-19 among children with asthma were also evaluated.

resultsOne hundred eighty-nine patients who had COVID-19, and 792 who did not were included in the study. Fever, fatigue, and cough were the most frequent symptoms during COVID-19. Regarding the severity of COVID-19, 163 patients (87.6%) had a mild clinical condition, 13 (7%) had moderate disease, 1 (0.5%) had severe disease, and 2 had (1.1%) critically ill disease. Two patients were diagnosed with multisystem inflammatory syndrome in children (MIS-C), one patient suffered from pneumothorax. LFTs of the patients before and after COVID-19 infection were analyzed; no significant differences were found in FEV

conclusionCOVID-19 infection leads to dysfunction of the small airways in asthmatic children and obesity is an independent risk factor for a ≥25% decrease in FEF25-75. The long-term effects of COVID-19 infection especially on small airways require close monitoring in children with asthma.

Indexed as

AsthmaCOVID-19ChildHumansLungObesityRetrospective StudiesRisk FactorsSARS-CoV-2Systemic Inflammatory Response SyndromeasthmachildhoodCOVID-19obesitysmall airway dysfunction

Identifiers

PMID35502514
PMCPMC9347415
OpenAlexW4225425417

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.