Trial reportBioMed research international2022
The Effect of Flowable Composite Resins on Periodontal Health, Cytokine Levels, and Immunoglobulins.
Trial report in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05476848 (Evaluation of Oral Health Status and Cytokine Levels in Sars-Cov-2 Hospitalized Patients), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Oral Health Status and Cytokine Levels in Sars-Cov-2 Hospitalized Patients: A Randomized Clinical Trial
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Clinical performance of self-adhesive resin composite direct restorations in permanent teeth: a systematic review and meta-analysis.Clinical oral investigations · 2025Pooled it
- Effect of deep margin elevation with different base materials on periodontal health in a clinical study.Scientific reports · 2026Article
- Self-Adhesive Flowable Resin Composites-Are We Going Somewhere?Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Review
- Selected Properties of Composite Materials Used for Dental Fillings-Methodological Development and Preliminary Results.Materials (Basel, Switzerland) · 2025Article
- Fixation of Flowable Composite Resin Within Crossing Sutures for the Closure of Oroantral Communications: Two Clinical Cases and Literature Review.Case reports in medicine · 2025Article
- Cytotoxicity and reactive oxygen species production induced by different co-monomer eluted from nanohybrid dental composites.BMC oral health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study investigated the effects of flowable resin composites (FCR) on the restoration of noncarious cervical lesions (NCCL) and their impact on periodontal tissues. Materials and Methods: 30 periodontally healthy patients were assigned into three groups randomly; group VF: self-adhering FCR, group NF: fluoride-releasing FCR, and group SF: microhybrid FCR. Gingival crevicular fluid (GCF) volume levels of osteoprotegerin (OPG), immunoglobulins (IgA, IgM), and interleukins (IL-1, IL-1 Results: The GCF volume was increased mostly in group SF (1.34 ± 0.09 Conclusions: Clinical efficacy of self-adhering FCR was found the best for restoration of NCCL while fluoride-releasing FCR stimulated the periodontal response and had negative effects on GCF volume, cytokine, and immunoglobulin levels.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.