Evidence map›Paper›PMID 35502089›Full record

ArticleIndian journal of ophthalmology2022

Necrosis of uveal melanoma post-COVID-19 vaccination.

Ajeet M Wagle, Bing Cheng Wu, Lingam Gopal, Gangadhara Sundar

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ajeet M WagleInternational Eye Cataract Retina Centre, Mount Elizabeth Medical Centre and Farrer Park Medical Centre; Department of Ophthalmology and Visual Sciences, Khoo Teck Puat Hospital, Singapore.
Bing Cheng WuDepartment of Pathology, National University Hospital, National University of Singapore, Singapore.
Lingam GopalDepartment of Ophthalmology, National University Hospital, National University of Singapore, Singapore.
Gangadhara SundarDepartment of Ophthalmology, National University Hospital, National University of Singapore, Singapore.
National University Hospital · SGKhoo Teck Puat Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 49-year-old Indian male presented with rapidly progressive vision loss 1 day after receiving the second dose of BNT162b2 mRNA coronavirus disease 2019 (COVID-19) vaccine (Pfizer-BioNTech, NY, USA). The eye had secondary angle closure glaucoma, bullous retinal detachment, and massive intraocular hemorrhage. Ultrasound showed an ill-defined subretinal mass with moderate internal reflectivity. Magnetic resonance imaging (MRI) confirmed an enhancing heterogeneous subretinal mass. Histopathology showed a necrotic melanocytic lesion arising from the posterior edge of the ciliary body and choroid. Necrotic uveal melanoma was confirmed after expert histopathology opinion. Uveal melanomas can rarely present with tumor necrosis following mRNA COVID-19 vaccination.

Indexed as

COVID-19MelanomaBNT162 VaccineCOVID-19 VaccinesHumansMaleMiddle AgedNecrosisRNA, MessengerUveal MelanomaUveal NeoplasmsVaccinationBNT162 VaccineCOVID-19 VaccinesRNA, MessengerCOVID-19 vaccinationnecrotic melanomaspontaneous necrosisuveal melanoma

Identifiers

PMID35502089
PMCPMC9333048
OpenAlexW4225425577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.