Evidence map›Paper›PMID 35501884›Full record

Observational studyCritical care (London, England)2022

Cardiopulmonary resuscitation duration and favorable neurological outcome after out-of-hospital cardiac arrest: a nationwide multicenter observational study in Japan (the JAAM-OHCA registry).

Tasuku Matsuyama, Bon Ohta, Kosuke Kiyohara, Tetsuhisa Kitamura

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Critical care (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tasuku MatsuyamaDepartment of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan. task-m@koto.kpu-m.ac.jp.
Bon OhtaDepartment of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kosuke KiyoharaDepartment of Food Science, Otsuma Women's University, Tokyo, Japan.
Tetsuhisa KitamuraDivision of Environmental Medicine and Population Services, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.
Kyoto Prefectural University of Medicine · JPOsaka University · JPOtsuma Women's University · JP

Funding

Japan Society for the Promotion of Science 19K09393Japan Society for the Promotion of Science KAKENHI 21K16576
6 · The paper itself

Abstract

objectiveWe aimed to assess the association between cardiopulmonary resuscitation (CPR duration) and outcomes after OHCA.

methodsThis secondary analysis of a prospective, multicenter, observational study included adult non-traumatic OHCA patients aged ≥ 18 years between June 2014 and December 2017. CPR duration was defined as the time from professional CPR initiation to the time of return of spontaneous circulation or termination of resuscitation. The primary outcome was 1-month survival, with favorable neurological outcomes defined by cerebral performance category 1 or 2. We performed multivariable logistic regression analysis to investigate the association between CPR duration and favorable neurological outcomes. We also investigated the association between CPR duration and favorable neurological outcomes stratified by case features, including the first documented cardiac rhythm, witnessed status, and presence of bystander CPR.

resultsA total of 23,803 patients were included in this analysis. Multivariable logistic regression analysis demonstrated that the probability of favorable neurological outcomes decreased with CPR duration (i.e., 20.8% [226/1084] in the ≤ 20 min group versus 0.0% [0/708] in the 91-120 min group, P for trend < 0.001). Furthermore, the impact of CPR duration differed depending on the presence of case features; those with shockable, witnessed arrest, and bystander CPR were more likely to achieve favorable neurological outcomes after prolonged CPR duration > 30 min.

conclusionThe probability of favorable neurological outcome rapidly decreased within a few minutes of CPR duration. But, the impact of CPR duration may be influenced by each patient's clinical feature.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesOut-of-Hospital Cardiac ArrestAdultHumansJapanProspective StudiesRegistriesTime FactorsCardiopulmonary resuscitationCardiopulmonary resuscitation durationNeurological outcomesOut-of-hospital cardiac arrest

Identifiers

PMID35501884
PMCPMC9059367
OpenAlexW4225276403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.