Changes in the Expression of Pluripotency Factor Oct-4 and Intensity of Apoptosis in the Uterus during Spontaneous and Immune-Dependent Abortions in Mice.

K A Artem'eva, I I Stepanova, I M Bogdanova, M N Boltovskaya, N V Yaglova, S V Obernikhin, E A Ponomarenko

Abstract read

In one paragraph

Article in Bulletin of experimental biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 51% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

K A Artem'evaA. P. Avtsyn Research Institute of Human Morphology, Moscow, Russia. artemjeva_ksenia@mail.ru.

I I StepanovaA. P. Avtsyn Research Institute of Human Morphology, Moscow, Russia.

I M BogdanovaA. P. Avtsyn Research Institute of Human Morphology, Moscow, Russia.

M N BoltovskayaA. P. Avtsyn Research Institute of Human Morphology, Moscow, Russia.

N V YaglovaA. P. Avtsyn Research Institute of Human Morphology, Moscow, Russia.

S V ObernikhinA. P. Avtsyn Research Institute of Human Morphology, Moscow, Russia.

E A PonomarenkoA. P. Avtsyn Research Institute of Human Morphology, Moscow, Russia.

Research Institute of Human Morphology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the expression of pluripotency factor Oct-4 and the intensity of apoptosis in the uterus during spontaneous and immune abortions in mice. Increased expression of factor Bax and reduced protein Bcl-2 synthesis in cells of the decidual membrane and decreased Oct-4 expression in the myometrium and perimetrium were detected. Thus, both spontaneous and immune-dependent abortions impair the apoptosis processes in the decidua and the formation of a pool of Oct-4

Indexed as

Abortion, SpontaneousOctamer Transcription Factor-3UterusAnimalsApoptosisDeciduaFemaleHumansMicePregnancyOctamer Transcription Factor-3Pou5f1 protein, mouseapoptosismiscarriageOct-4pregnancyuterus

Identifiers

PMID35501657

DOI10.1016/j.ejogrb.2009.02.044

OpenAlexW4225403343

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Textmetadata

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.