Evidence map›Paper›PMID 35501656›Full record

ArticleBulletin of experimental biology and medicine2022

Diversity and Metabolic Potential of the Gut Microbiome in Adolescents with Functional Bowel Disorder.

E S Klimenko, N L Belkova, A I Romanitsa, A V Pogodina, L V Rychkova

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

E S KlimenkoResearch Center for Family Health and Human Reproduction Problems, Irkutsk, Russia. klimenko.elizabet@gmail.com.
N L BelkovaResearch Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
A I RomanitsaResearch Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
A V PogodinaResearch Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
L V RychkovaResearch Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
Scientific Center of Family Health Problems and Human Reproduction · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The article presents the results of a pilot study of the diversity and metabolic potential of the gut microbiome in adolescents with various forms of functional bowel disorder. The participants were the patients of the Clinic of Research Center for Family Health and Human Reproduction Problems. Biological material was studied using metagenomic sequencing of V3-V4 variable regions of the 16S rRNA gene. We showed that the composition of the minor component of the intestinal microbiome in adolescents with functional bowel disorder differs from that in the healthy subjects (control). Different types of transit disturbances in functional bowel disorder also differ from each other. According to the metabolic potential, adolescents can be divided into two groups irrespective of the pathophysiological manifestations: for one group, a more intensive metabolism in amino acid and lipid biosynthesis pathways was predicted than for the other.

Indexed as

Gastrointestinal MicrobiomeAdolescentFecesHumansMetagenomePilot ProjectsRNA, Ribosomal, 16SRNA, Ribosomal, 16Sadolescentsfunctional bowel disordersgut biocenosisopportunistic microbiota

Identifiers

PMID35501656
OpenAlexW4225407207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.