ArticleScientific reports2022
Mouse lung mechanical properties under varying inflation volumes and cycling frequencies.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Human airway material characterization via inverse finite element analysis and neural network surrogate.Biomechanics and modeling in mechanobiology · 2026Article
- Injury Mechanics in Surfactant-Depleted and Healthy Rat Lungs: A Multi-scale Consideration of Artificial and Physiological Ventilation.Annals of biomedical engineering · 2026Article
- Human ex-vivo lung mechanics differ under positive- and negative-pressure ventilation.Respiratory research · 2026Article
- Interactive effects of pulmonary pathologies and ventilation modes driving heterogeneous and anisotropic regional strain mechanics.Scientific reports · 2025Article
- Fibrotic and emphysematous murine lung mechanics under negative-pressure ventilation.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Lung recruitment mechanics: coalescing tissue strains with organ expansion.Respiratory research · 2025Article
- Towards constructing a generalized structural 3D breathing human lung model based on experimental volumes, pressures, and strains.PLoS computational biology · 2025Article
- A Comparative Study of Ex-Vivo Murine Pulmonary Mechanics Under Positive- and Negative-Pressure Ventilation.Annals of biomedical engineering · 2024Article
- Role of lung lobar sliding on parenchymal distortion during breathing.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- LungElast-an open-source, flexible, low-cost, microprocessor-controlled mouse lung elastometer.Scientific reports · 2023Article
- Effects of tissue degradation by collagenase and elastase on the biaxial mechanics of porcine airways.Respiratory research · 2023Article
- Diseased and healthy murine local lung strains evaluated using digital image correlation.Scientific reports · 2023Article
- Associating local strains to global pressure-volume mouse lung mechanics using digital image correlation.Physiological reports · 2022Article
- Mechanical properties of the premature lung: From tissue deformation under load to mechanosensitivity of alveolar cells.Frontiers in bioengineering and biotechnology · 2022Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory pathologies alter the structure of the lung and impact its mechanics. Mice are widely used in the study of lung pathologies, but there is a lack of fundamental mechanical measurements assessing the interdependent effect of varying inflation volumes and cycling frequency. In this study, the mechanical properties of five male C57BL/6J mice (29-33 weeks of age) lungs were evaluated ex vivo using our custom-designed electromechanical, continuous measure ventilation apparatus. We comprehensively quantify and analyze the effect of loading volumes (0.3, 0.5, 0.7, 0.9 ml) and breathing rates (5, 10, 20 breaths per minute) on pulmonary inflation and deflation mechanical properties. We report means of static compliance between 5.4-16.1 µl/cmH
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