Evidence map›Paper›PMID 35500898›Full record

ArticlePsychiatry investigation2022

Real-World Evidence for the Association Between Pneumonia-Related Intensive Care Unit Stay and Dementia.

Chun-Han Wu, Chung-Kan Peng, Chi-Hsian Chung, Wu-Chien Chien, Nian-Sheng Tzeng

Open access · diamondAbstract read
In one paragraph

Article in Psychiatry investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Infection trajectories and dementia risk in type 2 diabetes.Diabetology & metabolic syndrome · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chun-Han WuDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Chung-Kan PengDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Chi-Hsian ChungDepartment of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Wu-Chien ChienDepartment of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Nian-Sheng TzengDepartment of Psychiatry, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Tri-Service General Hospital · TW

Funding

Medical Affairs Bureau MAB-107-084Ministry of Defense of Taiwan MNDMAB- D-111-075Taoyuan Armed Forces General Hospital TYAFGH-A-110-020Tri-Service General Hospital Research Foundation TSGH-B-109-010Tri-Service General Hospital Research Foundation TSGH-B-111-018Tri-Service General Hospital Research Foundation TSGH-C108-003Tri-Service General Hospital Research Foundation TSGHC108-027Tri-Service General Hospital Research Foundation TSGH-C108-151Tri-Service General Hospital Research Foundation TSGH-D-111-121
6 · The paper itself

Abstract

objectiveThere is limited clarity concerning the risk of dementia after pneumonia with intensive care unit (ICU) stay. We conducted a nationwide cohort study, which aimed to investigate the impact of dementia after pneumonia with and without intensive care unit admission.

methodsData was obtained from Taiwan's National Health Insurance Research Database between 2000 and 2015. A total of 7,473 patients were identified as having pneumonia required ICU stay, along with 22,419 controls matched by sex and age. After adjusting for confounding factors, multivariate Cox regression model analysis was used to compare the risk of developing dementia during the 15-years follow-up period.

resultsThe enrolled pneumonia patients with ICU admission had a dementia rate of 9.89%. Pneumonia patients without ICU admission had a dementia rate of 9.21%. The multivariate Cox regression model analysis revealed that the patients with ICU stay had the higher risk of dementia, with a crude hazard ratio of 3.371 (95% confidence interval, 3.093-3.675; p<0.001).

conclusionThis study indicated that pneumonia with ICU stay is associated with an increased risk of dementia. A 3-fold risk of dementia was observed in patients admitted to the ICU compared to the control group.

Indexed as

DementiaIntensive carePneumonia

Identifiers

PMID35500898
PMCPMC9058270
OpenAlexW4224323892

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.